Question · Q4 2025
Albert Rice inquired about the seasonality of the $25 million-$35 million Stelara gross profit headwind for 2026, specifically whether it would be evenly distributed or if Q1 would be a tougher comparable due to 2025 forward buying. He also asked about AI applications beyond claims processing, such as clinician utilization, staffing, or inventory management.
Answer
EVP and CFO Meenal Sethna stated that the $25 million-$35 million Stelara headwind for 2026 is expected to be fairly evenly distributed, without the Q1 phenomenon seen in 2025, though the year-over-year Q1 comp will still be tougher. President and CEO John Rademacher detailed AI applications in call center capabilities, workforce optimization, and inventory management, noting that these tools augment the team's efficiency and quality. He clarified that AI is not yet used for clinical protocols but may support clinicians in areas like note capture.
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