Question · Q3 2025
Andy Shea inquired about Exelixis' strategy for navigating potential cannibalization between Cabozantinib and Zanzalintinib in the neuroendocrine tumor (NET) population, particularly as Cabozantinib entrenches in earlier line settings.
Answer
PJ Haley, EVP of Commercial, stated that the Zanzalintinib study in NETs is designed to position it competitively and upfront, but that is far down the road. In the near term, there is significant room for Cabozantinib in NETs to become a key player, given its strong launch and demand growth.
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