Question · Q4 2025
Brian P. Skorney asked about the commercial opportunity for BIIB080, an anti-tau ASO, considering the challenges faced by Leqembi as an IV, and what specific clinical data would be necessary to achieve a higher level of commercial success.
Answer
Christopher A. Viehbacher, President and CEO, Biogen, highlighted the neurology community's interest in tau as a target and BIIB080's ability to reduce tau. He emphasized the need to see the data on cognition and side effect profile, noting that positive results would excite the community but would still require a multi-year Phase III program. He also mentioned the potential for BIIB080 in other tauopathies and its role in a multi-modality approach to Alzheimer's.
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