Bryan Cheng's questions to Coherus Oncology (CHRS) leadership • Q4 2024
Question
Asked about LOQTORZI's real-world user stickiness, physician willingness to switch from off-label Keytruda, and what constitutes good data from the upcoming CCR8 intratumoral biopsies.
Answer
The company noted high physician satisfaction and repeat use of LOQTORZI, though opportunities are infrequent due to the rarity of NPC. They are actively working to convert off-label users with data and guideline education. Good biopsy data would show Treg depletion and an increase in CD8 T cells within the tumor.