Carly Kenselaar's questions to Innate Pharma (IPHA) leadership • Q3 2023
Question
Asked about the regulatory pathway for lacutamab in CTCL (Sezary syndrome and mycosis fungoides) and the development strategy and timelines for the Nectin-4 ADC program.
Answer
For lacutamab, the company will discuss the Sezary syndrome data with the FDA regarding a potential accelerated approval pathway, with a confirmatory Phase III trial likely to include mycosis fungoides. Further development will be pursued via partnership. For the Nectin-4 ADC, the strategy includes targeting patients post-PADCEV, leveraging a different payload (Topo I inhibitor), with an IND filing planned for the following year.