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    Catherine SchulteRobert W. Baird & Co.

    Catherine Schulte's questions to Natera Inc (NTRA) leadership

    Catherine Schulte's questions to Natera Inc (NTRA) leadership • Q2 2025

    Question

    Catherine Schulte asked for the timeline to secure Medicare coverage for the $250-$300 million opportunity in non-covered Signatera indications and questioned if the $150 million investment in breast cancer trials signals a strategic prioritization.

    Answer

    CEO Steve Chapman stated the $250-$300M opportunity is a key focus, with numerous submissions planned over the next 12-18 months. Regarding the breast cancer investment, he clarified that it has always been a major priority, with trials like DARE starting years ago, and the significant, budgeted investment creates a high barrier for competitors to replicate.

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    Catherine Schulte's questions to Natera Inc (NTRA) leadership • Q1 2025

    Question

    Catherine Schulte inquired about the timeline and path to reimbursement for Signatera in Japan and asked how the company's commercial strategy is evolving amidst a changing competitive landscape for MRD testing.

    Answer

    President of Clinical Diagnostics, Solomon Moshkevich, detailed the Japan timeline: PMDA approval is expected late 2025/early 2026, followed by a 6-9 month reimbursement process, with top-line impact anticipated in late 2026. CEO Steve Chapman addressed competition by stating that Natera's growth remains strong because physicians value its extensive clinical data, proven test performance, and long-term outcomes data, which he believes competitors lack, making Natera's offering superior.

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    Catherine Schulte's questions to Natera Inc (NTRA) leadership • Q4 2024

    Question

    Catherine Schulte from Baird inquired about the success rate in securing payment in states with biomarker bills and asked for a breakdown of the significant R&D spending increase planned for 2025.

    Answer

    President and Chief Business Officer, John Fesko, acknowledged that progress with biomarker bills has been gradual but noted recent formal policy publications from payers are positive signs that should drive improvement. CEO Steve Chapman explained the R&D increase is primarily focused on MRD (clinical trials, product extensions), with important investments also in Women's and Organ Health. He highlighted that the FDA-enabling study for early cancer detection (ECD) is a warranted new expense given the strong data and significant market opportunity.

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    Catherine Schulte's questions to Castle Biosciences Inc (CSTL) leadership

    Catherine Schulte's questions to Castle Biosciences Inc (CSTL) leadership • Q2 2025

    Question

    Catherine Schulte of Robert W. Baird & Co. inquired about the appropriate long-term growth assumption for DecisionDx Melanoma and the primary drivers of TissueCypher's growth, specifically new versus existing clinicians.

    Answer

    CFO Frank Stokes reiterated the high single-digit volume growth guidance for DecisionDx Melanoma for 2025 but did not provide a long-term forecast. CEO Derek Maetzold explained that due to low market penetration, TissueCypher's growth is being driven strongly by both new customer acquisition and deeper penetration within existing accounts.

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    Catherine Schulte's questions to Waters Corp (WAT) leadership

    Catherine Schulte's questions to Waters Corp (WAT) leadership • Q2 2025

    Question

    Catherine Schulte of Robert W. Baird & Co. asked for a breakdown of the $115 million in commercial excellence revenue synergies from the BD deal, specifically between the biosciences and diagnostics segments. She also questioned the company's confidence in being able to replicate its operational success with BD's underperforming microbiology business.

    Answer

    SVP & CFO Amol Chaubal clarified that instrument replacement synergies are largely on the biosciences side, while e-commerce and service attachment potential is spread across both businesses. President and CEO Dr. Udit Batra explained his confidence in turning around the microbiology business, noting the performance gap versus competitors is addressable through better pricing (enabled by a new product launch) and operational initiatives, which are not in the deal model.

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    Catherine Schulte's questions to Waters Corp (WAT) leadership • Q2 2025

    Question

    Catherine Schulte of Robert W. Baird & Co. requested a breakdown of the $115 million in commercial excellence revenue synergies from the BD deal between the biosciences and diagnostics businesses. She also asked for the basis of management's confidence in being able to turn around the underperforming BD microbiology business.

    Answer

    SVP & CFO Amol Chaubal clarified that instrument replacement synergies are largely on the biosciences side, while e-commerce and service attachment potential is spread across both businesses. President and CEO Dr. Udit Batra explained that the microbiology business's 180 basis point growth gap to its competitor is addressable through better pricing with the new Bactech launch (~100 bps) and operational initiatives (~80 bps). He stressed this turnaround potential is not in the deal's underwriting model.

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    Catherine Schulte's questions to Waters Corp (WAT) leadership • Q1 2025

    Question

    Catherine Schulte from Baird inquired about the outlook for China for the remainder of the year, including any customer hesitation and stimulus assumptions, and asked about the potential timing and cadence of reshoring tailwinds.

    Answer

    CEO Udit Batra reported that China grew 5% in Q1, ahead of expectations, but the forecast for the rest of the year prudently assumes low single-digit growth. Regarding reshoring, Batra noted it's 'early days' with no detailed customer plans yet, but Waters is well-positioned to benefit when capacity expansions occur. CFO Amol Chaubal added that the service organization's involvement in tech transfers provides early visibility.

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    Catherine Schulte's questions to Waters Corp (WAT) leadership • Q4 2024

    Question

    Catherine Schulte asked to quantify the Q4 budget flush impact on the Pharma segment's double-digit growth and inquired about the growth assumptions for Pharma in 2025. She also asked about the trajectory of service contract attachment rates.

    Answer

    President and CEO Dr. Udit Batra stated the Q4 revenue ramp was typical of pre-pandemic years (high-teens QoQ), reflecting a normalization of spending behavior in late-stage pharma. SVP and CFO Amol Chaubal noted that over 50% of the active installed base is now on a service plan, with nearly 60% covered including warranties, and the organization is now pivoting towards service-led lead generation.

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    Catherine Schulte's questions to Qiagen NV (QGEN) leadership

    Catherine Schulte's questions to Qiagen NV (QGEN) leadership • Q1 2025

    Question

    Catherine Schulte asked about business trends in China, comparing the diagnostics and life sciences segments, and inquired about the performance of QIAGEN Digital Insights (QDI) and its path to achieving its long-term growth targets.

    Answer

    CEO Thierry Bernard reiterated that China (4% of sales) is not a strategic priority due to its complexity and preference for local manufacturers, which impacts life sciences more than diagnostics like QuantiFERON. For QDI, he noted an encouraging Q1 with both discovery and clinical portfolios performing well. He guided to high single-digit growth for 2025 as the business completes its transition to a SaaS model, which positions it to achieve its long-term growth ambitions.

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    Catherine Schulte's questions to Mettler-Toledo International Inc (MTD) leadership

    Catherine Schulte's questions to Mettler-Toledo International Inc (MTD) leadership • Q1 2025

    Question

    Catherine Schulte from Baird asked for the value of imports into the U.S. from Switzerland to better assess potential country-specific tariff risks. She also inquired about the company's appetite to increase share buybacks given the current stock price.

    Answer

    CFO Shawn Vadala declined to provide a specific figure for Switzerland but stated that of the approximately $250 million in imports from Europe and the rest of the world, a 'significant portion' comes from Switzerland. He also affirmed that the company will stick to its previously stated share repurchase plan for the year, as they do not try to time the market.

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    Catherine Schulte's questions to Revvity Inc (RVTY) leadership

    Catherine Schulte's questions to Revvity Inc (RVTY) leadership • Q1 2025

    Question

    Catherine Schulte of Baird requested a quantitative breakdown of the tariff mitigation efforts between manufacturing shifts, cost actions, and pricing. She also asked about the latent TB test's exposure to immigration trends and any related concerns.

    Answer

    CFO Maxwell Krakowiak explained that supply chain and manufacturing adjustments account for the vast majority (75-80%) of the tariff mitigation, with the remainder coming from supplier changes and selective pricing. He also clarified that the latent TB business is more heavily indexed outside the U.S., so potential changes in U.S. immigration policy would not have a material impact on the company.

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    Catherine Schulte's questions to Twist Bioscience Corp (TWST) leadership

    Catherine Schulte's questions to Twist Bioscience Corp (TWST) leadership • Q1 2025

    Question

    Catherine Schulte of Robert W. Baird & Co. asked for details on the expected gross margin progression for the year and the impact of specific operational improvements, like the change in plastic tips.

    Answer

    An executive, likely CFO Adam Laponis, confirmed expectations for sequential quarterly improvements in gross margin, aiming to surpass 50% by Q4. President and COO Patrick Finn added that a pipeline of incremental improvements exists, highlighting the future use of proprietary enzymes to both drive new products and reduce internal costs.

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    Catherine Schulte's questions to Agilent Technologies Inc (A) leadership

    Catherine Schulte's questions to Agilent Technologies Inc (A) leadership • Q3 2024

    Question

    Catherine Schulte, under the name Catherine Ramsey, asked for the growth rate assumptions by business segment for the fourth quarter, as well as the outlook for small molecule pharma's performance excluding China.

    Answer

    CFO Bob McMahon and CEO Padraig McDonnell responded. Mr. McMahon provided Q4 guidance by segment: LSAG expected to be down low-single digits, DGG down mid-single digits, and ACG up mid-to-high single digits. Regarding small molecule pharma, Mr. McDonnell noted Europe was a standout performer. Mr. McMahon clarified that the segment was down mid-single digits globally but only down low-single digits when excluding China.

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    Catherine Schulte's questions to Exact Sciences Corp (EXAS) leadership

    Catherine Schulte's questions to Exact Sciences Corp (EXAS) leadership • Q2 2024

    Question

    Catherine Schulte inquired about the assumptions for care gap programs embedded in the full-year guidance, specifically their weighting between Q3 and Q4. She also asked for a timeline on when the pivotal samples for the blood-based screening test would be run and what preparatory steps are required.

    Answer

    CEO Kevin Conroy explained that care gap programs see a significant step-up in Q3 and an even larger one in Q4, as payers and health systems work to improve quality scores by year-end. CFO Aaron Bloomer confirmed this Q4 weighting and noted that revenue from these programs in H1 2024 already surpassed the full-year 2023 total. Regarding the blood test, Conroy detailed the extensive software validation, lab automation, and reagent QC work required before running the 10,000-20,000 pivotal samples, confirming they have not yet been processed and results are expected in Q4.

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    Catherine Schulte's questions to Bio-Techne Corp (TECH) leadership

    Catherine Schulte's questions to Bio-Techne Corp (TECH) leadership • Q2 2024

    Question

    Catherine Schulte inquired about the relative performance of reagents versus instrumentation in China and the expected trend in Q3. She also asked for a breakdown of RUO reagent growth between academic and pharma customers.

    Answer

    CFO Jim Hippel stated that reagent and instrument performance in China was comparably weak in Q2 but is expected to improve to modest positive growth in Q3, with similar trends for both categories. For RUO reagents, he noted that growth was also relatively comparable between academic and pharma customers, with slightly stronger performance in Europe for both.

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