Question · Q4 2025
Charles Ndiaye asked about the gating factors for initiating new Phase II studies for KT-621 beyond atopic dermatitis (AD) and asthma.
Answer
CEO Nello Mainolfi clarified that Kymera's strategy for KT-621 is to leverage the ongoing Phase IIb AD and asthma studies to support future registrational (Phase III) trials in other dermatologic and respiratory indications, respectively. He stated that the company does not plan to initiate new Phase II studies, aiming for all subsequent studies to be registrational.
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