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    Chris Pasquale

    Partner and Senior Analyst at Nephron Research LLC

    Chris Pasquale is a Partner and Senior Analyst at Nephron Research LLC, specializing in medical devices and supplies. He provides equity research coverage for major companies within the medical technology sector, leveraging deep industry knowledge to deliver actionable investment insights. Pasquale joined Nephron Research in 2022 and holds an established track record of high-quality, performance-driven analysis following prior experience at other leading firms. His professional credentials include industry-recognized securities licenses and regulatory registrations relevant to his analyst role.

    Chris Pasquale's questions to COOPER COMPANIES (COO) leadership

    Chris Pasquale's questions to COOPER COMPANIES (COO) leadership • Q3 2025

    Question

    Chris Pasquale from Nephron Research asked about the growth trajectory for MiSight into fiscal 2026, questioning if new launches could drive an acceleration or if growth would moderate due to a larger revenue base. He also requested a more specific outlook for CapEx next year and its growth relative to sales going forward.

    Answer

    President and CEO Al White suggested that MiSight's growth in 2026 would likely be more similar to this year's rate rather than an acceleration, given the larger base. CFO Brian Andrews stated that CapEx will decrease in both absolute dollars and as a percentage of revenue next year. He explained that while investment will continue, the peak spending cycle is over, allowing CapEx to normalize and help drive free cash flow higher, similar to historical levels.

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    Chris Pasquale's questions to COOPER COMPANIES (COO) leadership • Q2 2025

    Question

    Chris Pasquale questioned if the slowdown in contact lens market growth was simply pricing trends returning to historical norms and asked about future pricing power. He also inquired about the company's ability to mitigate potential tariff impacts by shifting manufacturing.

    Answer

    President & CEO Albert White asserted that market pricing remains solid and likely higher than pre-COVID levels due to inflation, attributing the current softness more to channel inventory adjustments. CFO Brian Andrews stated that Cooper has multiple levers to mitigate tariffs, including price increases and supply chain adjustments, but is taking a "wait and see" approach pending more clarity.

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    Chris Pasquale's questions to ALCON (ALC) leadership

    Chris Pasquale's questions to ALCON (ALC) leadership • Q2 2025

    Question

    Chris Pasquale of Nephron Research asked about the sustainable long-term revenue growth rate for STAAR's EVO ICL platform and questioned why Alcon's tariff headwind forecast increased while other companies saw theirs decrease.

    Answer

    CEO David Endicott expressed confidence in solid global growth for EVO, citing low penetration and Alcon's ability to accelerate adoption. CFO Tim Stonesifer explained the increased tariff forecast was due to rates coming in higher than expected, with mitigation currently relying heavily on favorable currency exchange rates while the company evaluates supply chain adjustments.

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    Chris Pasquale's questions to ZIMMER BIOMET HOLDINGS (ZBH) leadership

    Chris Pasquale's questions to ZIMMER BIOMET HOLDINGS (ZBH) leadership • Q2 2025

    Question

    Chris Pasquale from Nephron Research LLC questioned the confidence in the Monogram commercialization timeline, given the perceived regulatory hurdles for autonomous robotics, and asked how the deal would be EPS-neutral before generating revenue.

    Answer

    Chairman, President & CEO Ivan Tornos expressed high confidence, noting a 2.5-3 year diligence process, engagement with third-party experts, and a robust clinical trial plan. To achieve EPS neutrality, he explained the company is reallocating OpEx from non-core areas and leveraging existing R&D and operational platforms from the ROSA business.

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    Chris Pasquale's questions to PROCEPT BioRobotics (PRCT) leadership

    Chris Pasquale's questions to PROCEPT BioRobotics (PRCT) leadership • Q2 2025

    Question

    Chris Pasquale from Nephron Research LLC asked for details on the surgeon utilization curve and the key drivers behind the continued strength in international revenue.

    Answer

    EVP & CFO Kevin Waters explained that the utilization ramp is consistent, taking 3-4 quarters for a surgeon to reach the average. He noted a new focus on launching accounts with multiple surgeons to improve efficiency. For international sales, he confirmed the UK remains the primary driver of upside, with Japan and Korea showing promising early traction and representing a combined 70% of international revenue with the UK.

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    Chris Pasquale's questions to Axogen (AXGN) leadership

    Chris Pasquale's questions to Axogen (AXGN) leadership • Q2 2025

    Question

    Chris Pasquale from Nephron Research LLC asked about the primary drivers behind the strong Q2 revenue growth, which showed acceleration against a tougher comparison, and questioned the implied deceleration in the full-year guidance for the second half.

    Answer

    President and CEO Michael Dale attributed the robust growth to solid execution of their strategic plan, particularly the focus on high-potential accounts and the core value proposition of the Avance Nerve Graft. He highlighted that the extremities business was growing faster than internal plans. Regarding the conservative back-half guidance, Dale explained it was a prudent measure to account for potential logistical changes related to the BLA approval, which could affect how the company manages product supply for unscheduled procedures.

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    Chris Pasquale's questions to Inspire Medical Systems (INSP) leadership

    Chris Pasquale's questions to Inspire Medical Systems (INSP) leadership • Q2 2025

    Question

    Chris Pasquale from Nephron Research LLC questioned why the company's guidance follows typical seasonality given the unique headwinds peaking in Q3. He also asked about potential pushback from physicians regarding lower Medicare payment rates under the new CPT code.

    Answer

    CEO Tim Herbert acknowledged the Q3 guidance is softer than historical trends but maintained that the Q4 ramp-up remains consistent with past seasonality. On reimbursement, he addressed physician concerns by explaining that the reduced OR time with Inspire V should make the effective reimbursement-per-minute comparable. He also highlighted that the proposed 2026 Medicare rate increase significantly closes the payment gap between the old and new codes.

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    Chris Pasquale's questions to STRYKER (SYK) leadership

    Chris Pasquale's questions to STRYKER (SYK) leadership • Q2 2025

    Question

    Chris Pasquale of Nephron Research LLC asked if Stryker sees a limit to its 'one size fits all' Mako strategy compared to competitors' portfolio approaches. He also questioned the sustainability of double-digit trauma growth as comps for the Pangaea launch get tougher.

    Answer

    Chair & CEO Kevin Lobo stated that Stryker has a 'winning solution' with Mako and will continue its strategy of adding new applications to the single platform, without commenting on future pipeline developments. He expressed confidence in sustaining high growth in Trauma & Extremities, citing the ongoing, multi-faceted Pangaea launch, its upcoming European debut, and strong performance in upper extremities and total ankle.

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    Chris Pasquale's questions to STRYKER (SYK) leadership • Q1 2025

    Question

    Carol, on behalf of Chris Pasquale, asked about long-term steps to mitigate tariff exposure, such as manufacturing footprint changes, and inquired about the potential impact of recent FDA layoffs on product approvals.

    Answer

    CFO Preston Wells stated that no major changes to the manufacturing footprint are planned, as such moves are complex and lengthy, though the company is leveraging dual sourcing where possible. CEO Kevin Lobo assured that the FDA layoffs were largely and quickly reversed for industry-funded positions, and he does not anticipate any major slowdowns in product approvals.

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    Chris Pasquale's questions to TransMedics Group (TMDX) leadership

    Chris Pasquale's questions to TransMedics Group (TMDX) leadership • Q2 2025

    Question

    Chris Pasquale inquired about any substantive changes to the OCS Lung IDE trial design and sought commentary on the relatively flat U.S. heart transplant market.

    Answer

    CEO Waleed Hassanein confirmed the OCS Lung trial's clinical design is unchanged, with final FDA questions focused on preclinical data. He attributed the flat heart market to normal fluctuations and DCD non-progression rates, expressing confidence that the upcoming next-gen OCS Heart trial will be a significant growth catalyst.

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    Chris Pasquale's questions to Penumbra (PEN) leadership

    Chris Pasquale's questions to Penumbra (PEN) leadership • Q2 2025

    Question

    Chris Pasquale of Nephron Research asked for quantification of China's contribution to the strong international embolization results and for an updated full-year outlook for the Embolization & Access business.

    Answer

    CEO Adam Elsesser clarified that China does not order Penumbra's coil products, so the recent order had no impact on the embolization (Ambo) business results. He attributed the broader international strength to a multi-year rebuilding effort and new product introductions, expressing confidence in the segment's trajectory without providing a specific guidance update.

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    Chris Pasquale's questions to Edwards Lifesciences (EW) leadership

    Chris Pasquale's questions to Edwards Lifesciences (EW) leadership • Q2 2025

    Question

    Chris Pasquale from Nephron Research LLC asked about the practical reimbursement landscape for asymptomatic TAVR cases, questioning how local MACs are handling claims in the U.S. and what the reimbursement pathway looks like in Europe following the new indication.

    Answer

    Larry Wood, Corporate VP of TAVR, explained that while he is unaware of coverage issues for trial patients, some U.S. hospital systems are waiting for a formal NCD update, creating a 'slow burn' adoption. In Europe, he noted that the recent CE mark approval is the first step, and the company must now begin the country-by-country process of securing reimbursement, which will take time.

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    Chris Pasquale's questions to Edwards Lifesciences (EW) leadership • Q2 2025

    Question

    Chris Pasquale of Nephron Research LLC asked about the practical reimbursement landscape for asymptomatic TAVR cases with local MACs ahead of an NCD update. He also inquired about the process and timeline for securing broad reimbursement access in Europe following the recent CE Mark approval.

    Answer

    Corporate VP Larry Wood explained that while he is not aware of reimbursement issues for cases submitted to local MACs, some large hospital systems are waiting for a formal NCD update, creating a 'slow burn' adoption. For Europe, he noted the CE Mark approval was the critical first step, and the process of engaging with individual country reimbursement bodies has just begun.

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