Question · Q3 2025
Colleen asked about Ambry's performance, seeking clarification on the mix of growth drivers (share gains vs. organic expansion), how Ambry's growth compares to the broader hereditary cancer market (estimated low double digits), and the impact of panel mix (Cancer Next vs. targeted) on future ASPs.
Answer
CFO Jim Rogers stated that Ambry's growth was about 50% from share gains, similar to the prior quarter, but expects this to moderate to low- to mid-20s growth in Q4. CEO Eric Lefkofsky added that the hereditary space is stronger than previously thought, with Ambry's low- to mid-20s growth significantly above the estimated low double-digit industry growth due to its 'gold standard assays.' CFO Jim Rogers noted that ASPs have been consistent, down slightly year-over-year due to payer renegotiations, and that the rare disease business, though small, has a higher ASP and could impact overall ASPs as it scales.
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