David Huang's questions to Neurocrine Biosciences Inc (NBIX) leadership • Q2 2025
Question
David Huang of Deutsche Bank asked about the competitive implications of a competitor raising its guidance for its VMAT2 inhibitor and also inquired about the percentage of CAH patients who are regularly seen in clinics.
Answer
CEO Kyle Gano addressed the competitive question by focusing on INGREZZA's performance, highlighting its strong volume growth and market share gains in total prescriptions. On the CAH market, CCO Eric Benevich reiterated the estimate of over 20,000 prevalent patients in the U.S. and explained that a firm number is difficult to ascertain, as some patients are not managed by endocrinologists and the diagnosis code is not specific to classic CAH.