Dennis Chu's questions to RECURSION PHARMACEUTICALS (RXRX) leadership • Q1 2025
Question
Dennis Chu of Jefferies, along with analysts from Needham, Bank of America, and Cowen, asked for details on the FAP data, its differentiation from other programs, the case of the non-responder, and the bar for success.
Answer
Chief R&D Officer Najat Khan reported that preliminary data showed a 43% median polyp burden reduction, comparing favorably to the 20-30% seen with other agents. She noted the safety profile is consistent with the MEK1/2 inhibitor class. Regarding the non-responder, she explained that non-response rates of 40-50% have been seen in prior studies. The bar for success is high given the significant unmet need.