Devanjana Chatterjee's questions to KalVista Pharmaceuticals (KALV) leadership • Q1 2026
Question
Devanjana Chatterjee asked what payers would typically require in terms of safety or efficacy failure on Acadevant to approve ECTERLEET, particularly in cases where a generic step-through might be required. She also inquired if the company would share KPIs related to the percentage of patients covered in the future.
Answer
Nicole Sweeny, Chief Commercial Officer, explained that for the minority of patients (20%) without prior generic Acadevant experience, physicians find it simple to describe failure, citing reasons like injection site reactions or difficulties with sub-Q administration for abdominal attacks or hand swelling. She stated that future sharing of specific payer-related KPIs is yet to be determined, but the company recognizes the interest in providing more clarity on ongoing paid access and policy establishment.