Dipesh Patel's questions to SELB leadership • Q1 2023
Question
Dipesh Patel asked about the future of ImmTOR in gene therapy following the MMA study pause, the impact of market conditions on the Sobi relationship, the development strategy for ImmTOR IL, and for details on secondary endpoints and non-responder characteristics from the DISSOLVE studies.
Answer
CEO Carsten Brunn affirmed that ImmTOR is well-suited for gene therapy, which remains a partnering strategy, citing the recent Astellas deal. He stated the Sobi relationship is strong and unaffected by market conditions, driven by positive Phase III data. He clarified that Selecta intends to develop ImmTOR IL for liver diseases internally without a partner for now. Regarding the DISSOLVE data, he noted that analysis of secondary endpoints and non-responders is ongoing and will be shared at a future scientific conference.