Jarwei Fang's questions to Amylyx Pharmaceuticals Inc (AMLX) leadership • Q2 2025
Question
Jarwei Fang, on behalf of Jeff Meacham, asked about overcoming the lack of an ICD-10 code to demonstrate the PBH market need to payers and about the level of patient community awareness for the PSP and Wolfram syndrome trials.
Answer
Co-CEO & Co-Founder Josh Cohen noted that work on an ICD-10 code is active and that claims analysis supports their market estimates. He highlighted the significant unmet need conveyed by physicians. Chief Medical Officer Dr. Camille Bedrosian added that the PSP patient community is very supportive, and Cohen mentioned growing awareness and referrals for Wolfram syndrome.