Question · Q3 2025
Jon Block asked for more details on Elanco's aspirations for a 'cleaner label' for Zenrelia in the U.S., including the timing and necessary steps, drawing a comparison to Zenrelia's higher market share gains in international markets despite shorter launch periods. He also inquired about the 2025 EBITDA guidance, the impact of incremental OpEx investments, and how these investments might continue into 2026.
Answer
Jeff Simmons, President and CEO, highlighted Zenrelia's double-digit market share in Japan, Canada, and Brazil, attributing it to the product's efficacy profile and strong testimonials in a double-digit growing dermatology market. He detailed a multi-pronged regulatory approach, including the recent removal of vaccine-induced disease language and a new data submission to the FDA to further align the U.S. label with international non-restrictive labels. Simmons noted the positive impact of the September label update, with increased clinic adoption and a nearly 50% rise in monthly sales per clinic since Q1. Bob VanHimbergen, CFO, confirmed the raised EBITDA guidance, attributing it to Q3 outperformance and strategic incremental OpEx investments in launches. He stated that Elanco would continue a data-driven 'no-regrets approach' to investments, expecting top-line, EBITDA, and EPS growth in 2026.