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    Joshua Schimmer

    Research Analyst at Evercore ISI

    Joshua Schimmer is a Senior Managing Director and leader in biotechnology equity research, most recently serving on Evercore ISI's Biotechnology Research Team where he specializes in coverage of small-, mid-, and select large-cap biotech companies. He consistently ranks as one of Wall Street's top biotech analysts, earning the No. 1 spot in Institutional Investor's All-America Research Team for five consecutive years, with additional recognition from TipRanks and other industry platforms for strong investment performance and high success rates. Schimmer began his analyst career at Cowen & Co., subsequently holding senior roles at Leerink Partners, Lazard Capital Markets, Piper Jaffray, and Evercore ISI before joining Cantor Fitzgerald in 2023; he also spent time on the buy-side with Davidson Kempner. He holds an M.D. from the University of Toronto with subspecialty medical training in internal medicine and rheumatology, as well as an MBA from Harvard Business School, and maintains relevant industry credentials and professional licenses.

    Joshua Schimmer's questions to ARS Pharmaceuticals (SPRY) leadership

    Joshua Schimmer's questions to ARS Pharmaceuticals (SPRY) leadership • Q1 2025

    Question

    Joshua Schimmer of Cantor Fitzgerald asked for guidance on the long-term cost of goods sold (COGS) for neffy and clarification on whether the 57% of commercial lives with access require prior authorization.

    Answer

    President and CEO Richard Lowenthal clarified that the 57% commercial coverage is without prior authorization, noting that coverage with prior authorization is near 90%. CFO Kathleen Scott added that COGS will increase slightly over the next 18 months as the zero-cost inventory expensed pre-approval is utilized.

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    Joshua Schimmer's questions to ARS Pharmaceuticals (SPRY) leadership • Q3 2024

    Question

    Joshua Schimmer of Evercore ISI asked about ARS Pharmaceuticals' expectations for neffy's gross-to-net adjustments, guidance for Q4 launch performance, the impact of inventory stocking, and the timeline for data from the chronic spontaneous urticaria (CSU) trial.

    Answer

    Executive Richard Lowenthal stated that gross-to-net expectations remain around 50%. While declining to provide specific Q4 guidance, he expressed strong optimism about early sales trends, noting that initial distributor inventory stocking was modest but is now accelerating. For the CSU trial, he anticipates patient dosing to begin in early 2025, with data expected by early 2026.

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    Joshua Schimmer's questions to NEUROCRINE BIOSCIENCES (NBIX) leadership

    Joshua Schimmer's questions to NEUROCRINE BIOSCIENCES (NBIX) leadership • Q1 2025

    Question

    Joshua Schimmer questioned whether INGREZZA's current contracting strategy anticipates the future impact of competitor AUSTEDO's IRA price negotiation and if the expanded sales force's contribution materialized earlier than expected.

    Answer

    CEO Kyle Gano stated that while the primary goal of contracting is patient access, the IRA is a growing variable that the company is monitoring, particularly with an eye on competitors' situations in 2027. Chief Commercial Officer Eric Benevich clarified that the sales force's positive impact was in line with expectations, as it took a few quarters for the new team to become fully productive.

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    Joshua Schimmer's questions to Krystal Biotech (KRYS) leadership

    Joshua Schimmer's questions to Krystal Biotech (KRYS) leadership • Q4 2024

    Question

    Joshua Schimmer requested quantification of the annual VYJUVEK price cap's impact in 2024 and 2025, and asked about new language in the 10-K regarding manufacturing process changes for the drug.

    Answer

    Christine Wilson, SVP and Head of U.S. Sales and Marketing, stated that approximately 8% of commercial patients have consistently been subject to the cap. Suma Krishnan, President of R&D, explained the manufacturing change was a successful and FDA-approved scale-up to a larger bioreactor, a process which de-risks CMC for the entire pipeline.

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