Question · Q3 2025
Keith Hinton asked about the XGen volumes, noting they seemed to slightly exceed internal expectations based on the H2 2025 volume split discussed in the Q2 call. He inquired where GeneDx outperformed internal expectations and why the full-year guide remained unchanged despite the beat. Hinton also asked about the general pediatrician launch, specifically regarding the back-end build-up (e.g., additional billing/revenue cycle staff, DTC spend) and any concerns about potential bottlenecks in genetic counseling for patients with variants.
Answer
Kevin Feeley, CFO, stated that the outperformance in XGen volumes was primarily driven by the outpatient side of the business, particularly from farming the pediatric neurologist call point, and noted strong momentum throughout Q3. He explained that the full-year guide was maintained to reflect a balanced view. Regarding the general pediatrician launch, Feeley confirmed that investments in back-end support, including genetic counseling resources and other support for non-experts, are core to the experience design changes. He reiterated that these investments are covered by ample gross margin, ensuring the business remains profitable on an adjusted basis.