Lily Young's questions to Ionis Pharmaceuticals Inc (IONS) leadership • Q1 2025
Question
Lily Young, on for Mani Foroohar, asked for more detail on the distribution of TRYNGOLZA patients between newly and previously diagnosed, and how that mix is expected to evolve.
Answer
Chief Global Product Strategy Officer Kyle Jenne stated that while specific patient numbers would not be disclosed, the company is encouraged by new patient identification and expects incremental additions quarterly. CEO Brett Monia clarified that going forward, growth depends on identifying new patients, as the initial bolus of known and clinical trial patients has been largely addressed. Chief Commercial Officer Jonathan Birchall added that growing awareness is motivating physicians to diagnose more actively.