Question · Q3 2025
Madeline, on behalf of Matt Pips, asked for rough timelines for completing the pivotal cohort in pediatric ALL and the total market opportunity across both adult and pediatric ALL patients.
Answer
Dr. Christian Itin, CEO of Autolus Therapeutics, estimated the pediatric ALL market opportunity in the US and Europe to be around 1,000 patients, with a significant proportion in the high-risk category. He projected that the phase two portion of the pediatric study could enter the follow-up period in 2027, with data potentially available in late 2027 or early 2028.
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