Question · Q3 2025
Mary Kate asked about the patient and physician feedback regarding the increasing duration of ARCALYST therapy, specifically from longer-term users.
Answer
John Paolini (CMO, Kiniksa Pharmaceuticals) discussed the academic literature's appreciation for disease duration and the necessity of long-term treatment, citing a 99.5% reduction in event rates with continuous therapy. Ross Moat (Chief Corporate and Commercial Officer, Kiniksa Pharmaceuticals) added that healthcare professionals appreciate the high access rates and quick patient onboarding, while patients report high satisfaction due to ARCALYST's efficacy and tolerability as a long-term treatment for a chronic disease.