Question · Q3 2024
Matthew Baer inquired about patient retention strategies for the ALPHA3 trial, specifically asking why a patient randomized to the 'watch and wait' control arm would choose to remain in the study.
Answer
Dr. David Chang, President and CEO, explained that 'watch and wait' is the current standard of care, and patients in the trial receive the best available care. He noted that investigators are confident in their ability to retain patients. Furthermore, if a patient in the control arm progresses and seeks another treatment, this is captured as a primary 'event' for the study's event-free survival endpoint, thus maintaining the trial's integrity.
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