Miriam Funt's questions to Immunovant Inc (IMVT) leadership • Q3 2024
Question
Miriam Funt of JPMorgan Chase & Co. asked how the recently presented extrathyroidal benefits in Graves' disease read through to the ongoing Thyroid Eye Disease (TED) trial and questioned the updated timeline for the TED data readout. She also inquired about the potential for FcRn inhibitors to move into earlier lines of RA treatment.
Answer
Executive Peter Salzmann explained that seeing proptosis changes in a Graves' population with mostly mild TED is encouraging for the broader strategy of treating TED earlier. He confirmed the TED data is now expected in the second half of next year due to competition for patients in the narrow trial slice. Dr. Peter Taylor addressed the RA question, stating that while theoretically possible, the prevalence of cheaper biosimilars and generics makes it likely that new therapies will focus on the high unmet need in the difficult-to-treat population.