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Morgan on for Sean Laaman

Research Analyst at Morgan Stanley

Morgan on for Sean Laaman's questions to ARGENX (ARGX) leadership

Question · Q4 2025

Morgan asked about the sustainability of VYVGART's growth profile, given $4.2 billion in net sales and 90% year-over-year growth, and its first year of operating profitability, as penetration deepens in MG and CIDP.

Answer

Karen Massey, COO, affirmed the building of a long-term, sustainable business. Karl Gubitz, CFO, stated that revenue growth is expected to exceed OpEx growth, leading to increasing operating margins over time. He highlighted the strong balance sheet with $4.4 billion in cash, which is expected to increase, supporting long-term, profitable growth.

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