Naz Rahman's questions to Talphera Inc (TLPH) leadership • Q2 2025
Question
Naz Rahman from Maxim Group asked for the basis of the company's confidence in activating new clinical sites on schedule and whether the recent enrollment acceleration was driven by better site selection or by drug shortages.
Answer
Chief Medical Officer Dr. Shakil Aslam stated that confidence in site activation comes from vetting new sites on their historical timelines and improving internal processes. CEO Vincent Angotti added that several new sites are already in the final stages of activation. Both executives clarified that the enrollment acceleration is a direct result of shifting to a new site profile with nephrologist PIs in medical ICUs, who are more engaged with CRRT. Dr. Aslam asserted that the spike is due to PI enthusiasm and the right patient population, not the ongoing drug shortages.