Question · Q4 2025
Philip Chickering asked for quantification of the Stelara impact in Q4 2025 to model gross profit growth excluding this factor. He also inquired about the expected acute and chronic growth rates for 2026 and whether margins, excluding Stelara, would change compared to prior years.
Answer
EVP and CFO Meenal Sethna confirmed that the Stelara headwind in Q4 2025 was in line with expectations, around $20 million, impacting gross profit by over 100 basis points. President and CEO John Rademacher projected mid-single-digit growth for acute therapies and high single-digit to low double-digit growth for chronic therapies in 2026, despite Stelara headwinds. He noted that profit contributions for acute therapies are expected to be consistent, but a faster growth in chronic therapies might put some pressure on overall gross margin percentage.
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