Question · Q4 2025
Qize Ding noted petosemtamab is in Phase 2 for combination with pembrolizumab in first-line non-small cell lung cancer (NSCLC) and asked if this was a new trial started in Q4 2025, requesting high-level thoughts and expectations behind the study.
Answer
Chief Development Officer Judith Klimovsky confirmed that EGFR is a relevant target for lung cancer. She explained that the study was planned as a signal-seeking trial in indications where Cetuximab showed maximum benefit, and in combination with pembrolizumab due to the known synergy between petosemtamab and pembrolizumab. Klimovsky stated it is a signal-seeking study and updates will be provided when data becomes available.
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