Question · Q3 2025
RK asked for a breakdown of the $830 million EscharEx peak sales projection between DFU and VLU opportunities. He also inquired about the status and timing of the BARDA RFP, and the impact of not having a permanent CPT code for NexoBrid on adoption, as well as the benefits a permanent code would bring.
Answer
Barry Wolfenson, EVP of Strategy and Corporate Development, explained that the DFU and VLU opportunities for EscharEx are roughly even, with a slight weighting towards VLU due to the pain associated with venous leg ulcers. Ofer Gonen, CEO, confirmed that the BARDA RFP for a 10-year contract (stockpiling, room-temp stable formulation, trauma/blast injury) is awaiting contract signing, with activities paused due to the government shutdown but expected to resume soon. Barry Wolfenson added that while NexoBrid has a temporary CPT code, a permanent one would enhance national and institutional legitimacy, standardize language, and ease approval pathways, thereby boosting physician and burn center adoption.
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