Rohin Patel's questions to Neuropace Inc (NPCE) leadership • Q2 2025
Question
Rohin Patel from JPMorgan Chase & Co. inquired about NeuroPace's FDA submission strategy for its Idiopathic Generalized Epilepsy (IGE) indication, asking if the company would pursue a broad label or a more segmented one. He also questioned the outlook for gross margin, noting the updated guidance implies a second-half decline despite strong Q2 performance.
Answer
CEO Joel Becker confirmed the strategy is to pursue a broad IGE indication for the entire patient population, citing the compelling and statistically significant data from pre-specified secondary endpoints. CFO Patrick Williams addressed the gross margin guidance, explaining it reflects prudence and not an expected decline. He highlighted that the core RNS System gross margin is already above 80% and that the company is on a path to achieve this level overall after the lower-margin Dixie Medical business is phased out. Williams also noted that the recent debt refinancing would save approximately $2 million in annual cash interest, aiding the path to cash flow breakeven.