Question · Q3 2025
Sean asked about the potential impact of several bispecific programs being developed in first-line colorectal cancer (CRC) on the later-line uptake of Atezolizumab plus Zanzalintinib, and sought clarification on why the Stellar-303 filing couldn't have been earlier.
Answer
Michael Morrissey, President and CEO, stated that it's difficult to comment on the impact of emerging bispecifics without pivotal trial data. He clarified that the Stellar-303 filing was delayed because no new NDAs or BLAs are being filed while the government is closed, and Exelixis hopes to file as soon as it reopens.
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