Sebastian Vandishot's questions to Valneva (VALN) leadership • Q2 2025
Question
Sebastian Vandishot of Van Lanschot Kempen inquired about the specifics of the upcoming Lyme disease vaccine data readout, asking whether to expect top-line data only or more detailed results, and how the vaccine's immunogenicity compares to past vaccines from the 1990s.
Answer
CEO Thomas Lingelbach explained that data reporting is Pfizer's responsibility and will likely occur in two steps: top-line efficacy data first, followed by detailed results by the end of Q1 2026. He noted that direct immunogenicity comparisons to older vaccines are scientifically difficult due to different trial designs and assays, but internal animal models showed non-inferiority or superiority, with the final efficacy data being the key determinant.