Question · Q4 2024
Seema Sheoran, on for Liisa Bayko, asked about the target product profile for avoralstat in diabetic macular edema (DME) and what investors should look for in the upcoming Phase 1 data.
Answer
Chief Commercial Officer Charlie Gayer outlined the target profile as an infrequent injection, potentially every 3-6 months, for the nearly 50% of DME patients who do not fully respond to anti-VEGF therapies. Chief R&D Officer Dr. Helen Thackray added that the Phase 1 trial will enroll patients directly to assess safety, tolerability, and initial signs of activity, such as changes in edema and visual acuity, after a single injection.
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