Question · Q4 2025
Shannon Duffy asked about the current refill rates for VYKAT XR, especially with a larger proportion of patients on the drug for several months, and how the average weight of new patients might change over time, particularly with an increase in older patients.
Answer
Anish Bhatnagar, Chairman and CEO, explained that the average weight of new patients is likely higher than in clinical trials, with more older patients (27-45 years) coming on therapy, suggesting a gentle increase in average weight over time. Meredith Manning, Chief Commercial Officer, expressed satisfaction with high adherence and refill rates as patients settle into optimal doses.
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