Sushila Hernandez's questions to Pharming Group (PHAR) leadership • Q2 2025
Question
Sushila Hernandez inquired about the expected timeline and potential bottlenecks for converting patients with a variant of uncertain significance (VUS) to paid Joenja therapy. She also asked for a geographic breakdown of the 185 APDS patients currently in access programs.
Answer
CEO Fabrice Chouraqui explained that the VUS reclassification will occur over time as diagnostic labs apply new data, with an estimated 20% of the 1,400 identified VUS patients ultimately being reclassified. Chief Medical Officer Anurag Relan added that Pharming has experience with this process and anticipates quick reimbursement post-reclassification. Fabrice Chouraqui declined to provide a country-specific breakdown of patients in access programs at this stage.