Thomas Bowers's questions to Zealand Pharma A/S/ADR (ZLDPF) leadership • Q3 2024
Question
Thomas Bowers asked if CRP reduction data was available from the petrelintide Phase I trial, questioned the strategy for the petrelintide/GLP-1 combination trial, and asked if the petrelintide weight loss curve was showing signs of plateauing.
Answer
CEO Adam Steensberg responded. He confirmed CRP data was not a part of the small Phase I study but is an expected effect. For the combination trial, the strategy is to add a small amount of GLP-1 on top of an effective dose of petrelintide for a more patient-friendly approach. Mr. Steensberg firmly disagreed that the weight loss curve was tailing off, attributing its shape to the low-BMI population and short study duration, and expressed no concerns about reaching long-term weight loss targets.