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    Thomas (for Ed Arce)H.C. Wainwright & Co.

    Thomas (for Ed Arce)'s questions to Mirum Pharmaceuticals Inc (MIRM) leadership

    Thomas (for Ed Arce)'s questions to Mirum Pharmaceuticals Inc (MIRM) leadership • Q4 2024

    Question

    Thomas, on behalf of Ed Arce, asked for the data timeline for the VISTAS study post-enrollment, patient experience in the EXPAND study, and if an interim analysis is planned for EXPAND.

    Answer

    CEO Chris Peetz estimated VISTAS top-line data would be available about six months after enrollment completion. CMO Joanne Quan cited positive compassionate use data in biliary atresia as a source of confidence for EXPAND and explicitly stated no interim analysis is planned, as it would delay full enrollment completion in 2026.

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