Trung Huynh's questions to Acumen Pharmaceuticals (ABOS) leadership • Q2 2025
Question
Trung Huynh asked how blood-based markers for identifying asymptomatic patients would be integrated into clinical practice and what the outlook is for payer coverage.
Answer
Chief Medical Officer Dr. Eric Siemers explained that payers are anecdotally already reimbursing for the FDA-approved pTau217 blood test. He anticipates this will continue for drugs proven effective in a preclinical population, as delaying cognitive decline presents a strong value proposition for payers by deferring higher healthcare costs. However, he stressed that clinical studies must first demonstrate this strategy's effectiveness.