Vik Chopra's questions to Neuropace Inc (NPCE) leadership • Q2 2025
Question
Vik Chopra from Wells Fargo & Company questioned whether the preliminary data from the NAUTILUS trial had created any negative commercial impact or tainted physicians' views of the RNS System. He also asked the new CFO, Patrick Williams, for his perspective on the achievability of the company's long-range plan (LRP) targets.
Answer
CEO Joel Becker stated there has been "absolutely no" negative commercial impact from the NAUTILUS data. He noted that investigators close to the trial are enthusiastic, as they recognize the primary endpoint miss was due to a statistical analysis method and that the secondary endpoints show highly statistically significant and clinically meaningful seizure reduction. CFO Patrick Williams expressed high conviction in achieving the LRP's target of 20%+ CAGR for the core RNS business, even without new indications. Becker added that the business is already delivering this growth and has the potential to do more.