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    William Ruby • TD Cowen

    William Ruby's questions to Pacific Biosciences of California Inc (PACB) leadership

    William Ruby's questions to Pacific Biosciences of California Inc (PACB) leadership • Q1 2025

    Question

    William Ruby from TD Cowen asked for details on demand trends in the EMEA region and inquired about the key drivers for achieving positive free cash flow by the end of 2027.

    Answer

    Christian Henry, President and CEO, stated that EMEA is expected to be the fastest-growing region, driven by strong Revio uptake in the rare disease market. To reach cash flow positive by the end of 2027, Henry outlined three pillars: top-line revenue growth from existing and new products, gross margin expansion, and disciplined expense management, citing the recent restructuring as a key step.

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    William Ruby's questions to Personalis Inc (PSNL) leadership

    William Ruby's questions to Personalis Inc (PSNL) leadership • Q4 2024

    Question

    William Ruby from TD Cowen questioned whether Personalis anticipates needing to access the capital markets in 2025, given the guided cash usage of $75 million to $80 million.

    Answer

    CFO Aaron Tachibana stated that the company has sufficient capital on its balance sheet to reach cash flow breakeven and has no specific need to raise additional capital. He added that they would evaluate opportunities if further investment were needed for strategic areas like clinical evidence generation.

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