Question · Q4 2025
Yun Zheng asked if it is reasonable to expect the once-weekly TransCon PTH program to enter the clinic in 2026 or if there is no need to rush. He also inquired about the most efficient clinical pathway to approval, given the goal of matching the PK profile to the daily YORVIPATH product.
Answer
Jan Møller Mikkelsen, President and Chief Executive Officer, explained that if the PK profile in healthy volunteers or hypopara patients demonstrates bioequivalence to Europat's daily dose over the entire week, it would significantly simplify and expedite the clinical trial process, ensuring expected safety and tolerability. This bioequivalence is the program's aspiration.
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