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Eric Crombez

Director at ABEONA THERAPEUTICSABEONA THERAPEUTICS
Board

About Eric Crombez

Eric Crombez, M.D., age 52, is an independent director of Abeona Therapeutics (ABEO) who joined the Board on August 8, 2024; he is a Class 2 director with a term expiring at the 2027 annual meeting . He is currently Chief Medical Officer and Executive Vice President at Ultragenyx, and is a board‑certified clinical geneticist with prior academic and industry roles spanning UCLA, Shire’s Human Genetics Therapy unit, and Dimension Therapeutics . The Board has determined Dr. Crombez is independent under Nasdaq rules .

Past Roles

OrganizationRoleTenure/DatesCommittees/Impact
Dimension TherapeuticsChief Medical OfficerLed clinical development for gene therapy programs in hemophilia B/A, OTC deficiency, and GSDIa
Shire (Human Genetics Therapy unit)Executive in HGT business unitIndustry leadership experience in rare disease/genetics
UCLA School of MedicineAssistant Professor, Pediatrics (Medical Genetics)Clinical/biochemical genetics training; academic credentials

External Roles

OrganizationRoleStatusScope/Responsibilities
UltragenyxChief Medical Officer & EVPCurrentLeads clinical development and translational research; oversees Clinical Development, Clinical Operations, BioMetrics, Endpoint Development & Strategy, Regulatory Affairs, and Drug Safety/Pharmacovigilance
Epicrispir BiotechnologiesIndependent Board MemberCurrentIndependent director role at another biotechnology company

Board Governance

  • Independence: The Board determined Dr. Crombez is independent under Nasdaq rules .
  • Committee assignments: Not listed as a member of Audit, Compensation, or Nominating & Corporate Governance Committees in the 2025 proxy (committees composed of Alvino/Alland/Wuchterl; Alvino/Alland/Charles; and Charles/Alland/Wuchterl, respectively) .
  • Attendance: Board held 14 meetings in 2024; each director attended 85% or more of Board and applicable committee meetings during their period of service .
  • Board leadership context: Chairman is Michael Amoroso; CEO is Vishwas Seshadri; no Lead Independent Director .
  • Tenure/classification: Class 2 director; term runs until the 2027 annual meeting .
  • Trading/hedging policy: Directors may not engage in short sales, options/derivatives, hold stock on margin, or pledge Company stock as collateral .
  • Related-party transactions oversight: Audit Committee reviews/approves such transactions; none in 2024 .

Fixed Compensation

Item2024 AmountNotes
Cash fees paid (pro‑rated for service starting Aug 2024)$19,231Director cash compensation in 2024 for Dr. Crombez
Standard annual Board cash retainer (policy)$50,000Paid in cash quarterly (non‑employee directors)
Committee membership fee per committee (policy)$7,500Paid in cash quarterly (per committee served)
Additional cash for Board Chairman (policy)$30,000Only for Chairman of the Board; no other committee chair fees

Performance Compensation

AwardGrant DateShares/UnitsGrant‑Date Fair ValueVesting
Restricted stock (pro‑rated newcomer grant)Aug 13, 202411,044$54,999Pro‑rated director equity; (Company policy: annual director equity awards vest one year after grant)
Annual director equity award policy2024 (incumbents)23,611 (7/8) and 11,797 (8/26)$181,048 totalAnnual director restricted stock vests one year after grant

Other Directorships & Interlocks

CompanyRolePublic/PrivateNotes
Epicrispir BiotechnologiesIndependent Board MemberDisclosed as an external directorship
  • Related-party/Interlock risk: No related-party transactions disclosed for 2024; Audit Committee reviews any such transactions .

Expertise & Qualifications

  • Board‑certified clinical geneticist; residencies in pediatrics and medical genetics; fellowship in clinical biochemical genetics at UCLA .
  • Education: B.S. in Biology (University of Michigan) and M.D. (Wayne State University School of Medicine) .
  • Therapeutic area leadership: Extensive clinical development leadership in rare disease and gene therapy (Ultragenyx; Dimension Therapeutics; Shire HGT) .

Equity Ownership

MetricAmountDate/As Of
Total beneficial ownership (common shares)47,145Record date March 24, 2025; under 1% of outstanding
Stock awards outstanding (unvested)11,044As of Dec 31, 2024
Pledging/HedgingProhibited by policyCompany policy prohibits pledging/hedging by directors

Governance Assessment

  • Positives: Independence affirmed; strong domain expertise in genetics and clinical development; equity alignment through restricted stock and personal ownership; Board‑level attendance thresholds met; use of an independent compensation consultant (Radford) with no conflicts reported enhances governance rigor .
  • Watch items: As a new director, no committee assignments yet—limits immediate committee‑level oversight influence . Abeona has no Lead Independent Director and maintains a staggered Board, governance features some investors view as reducing responsiveness . Time/attention risk: demanding full‑time CMO role at Ultragenyx plus external board service, though no related‑party transactions were reported for 2024 and independence is confirmed .