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Daniel O’Connell

Daniel O’Connell

Chief Executive Officer at Acumen Pharmaceuticals
CEO
Executive
Board

About Daniel O’Connell

Daniel O’Connell, age 55, is Chief Executive Officer of Acumen Pharmaceuticals (since December 2014) and a director (since April 2006). He co-founded Functional NeuroModulation Ltd. and was a founding member and former managing partner of NeuroVentures Capital, with a BA from Brown University and an MBA from the University of Virginia . In 2024, corporate performance goals tied to annual incentives were deemed 119% attained, supporting a maximum payout framework for the CEO’s bonus; his 2024 beneficial ownership was 2,657,738 shares (4.2% of outstanding), signaling meaningful alignment . Governance mitigates dual-role concerns: O’Connell is not independent and does not chair the board; the board is chaired independently by Sean Stalfort and the company separates the CEO and Chair roles .

Past Roles

OrganizationRoleYearsStrategic Impact
Functional NeuroModulation Ltd.Co-founder and CEONot disclosedClinical-stage deep brain stimulation therapies for Alzheimer’s disease
NeuroVentures Capital, LLCFounding member; former managing partnerNot disclosedEarly-stage neurosciences investing, deal flow and portfolio construction

External Roles

OrganizationRoleYearsStrategic Impact
NeuroVentures Capital, LLCFounding member; former managing partnerNot disclosedVenture capital network in neurosciences; sourcing and capital allocation

Fixed Compensation

Metric202320242025 (Approved)
Base Salary ($)$597,590 $621,494 $646,354
Target Bonus % of Salary55% (per CEO employment agreement) 55% Not separately disclosed; CEO remains eligible under committee process
Actual Annual Bonus ($)$427,277 $406,768 Not applicable

Director pay: O’Connell receives no additional compensation for board service .

Performance Compensation

ComponentMetric(s)WeightingTargetActualPayoutVesting Terms
Annual Cash Incentive (2024)Corporate goals in R&D, operational effectiveness, brand progress100% corporate for CEOCommittee-set (undisclosed) Corporate goals attained at 119% $406,768 Paid after year-end based on committee determination
RSUs (2024 grant)Time-based (no performance metric)N/A401,000 units N/AGrant-date FV $1,696,230 1/3 vested 1/2/2025; remaining 1/3 on 1/2/2026 and 1/2/2027, service-based
Stock Options (2024 grant)Time-based (no performance metric)N/A602,000 options N/AGrant-date FV $2,036,867 48 equal monthly installments from 1/2/2024 through 1/2/2028; exercise price $4.23; expires 1/2/2034

Notes:

  • Compensation program design and targets are set by an independent Compensation Committee (chair: Dr. Jeffrey Ives) advised by Aon; CEO excluded from his own pay deliberations .
  • No performance-vesting equity awards are disclosed; equity is time-based .

Equity Ownership & Alignment

ItemDetail
Total Beneficial Ownership2,657,738 shares; 4.2% of outstanding as of April 8, 2025
Composition136,755 common shares + 2,520,983 options exercisable within 60 days of 4/8/2025
Vested vs Unvested (12/31/2024)Unvested RSUs: 76,000 (2023 grant) and 401,000 (2024 grant); market value at $1.72/sh: $130,720 and $689,720
Options (key schedules)2019: 418,903 options, $0.72, fully vested ; 2021: 1,186,346 options ($1.19), 1/25 fully vested by 1/1/2025 ; 2022: 455,000 options ($5.19), monthly vesting through 1/19/2026 ; 2023: 472,500 options ($6.11), monthly vesting through 1/17/2027 ; 2024: 602,000 options ($4.23), monthly vesting through 1/2/2028
Hedging/PledgingInsider trading policy prohibits short sales, options, hedging transactions, and margin accounts . No pledges disclosed in beneficial ownership .
Ownership GuidelinesExecutive ownership guidelines not disclosed; director policy amended in 2025 to include RSUs in annual board grants .

Employment Terms

ProvisionCEO Terms
Agreement StatusAmended and restated employment agreement effective Jan 1, 2022
Base Salary & Bonus TargetBase initially $551,200; target bonus 55% of salary; current salary approved at $646,354 for 2025
Non-Compete / Non-SolicitNon-compete: 1 year post-termination; Non-solicit: 1 year post-termination; perpetual confidentiality and IP assignment
Severance (No CIC)12 months base salary + up to 12 months COBRA reimbursement, subject to release
Severance (With CIC – Double Trigger)If terminated without cause or resigns for good reason within 3 months pre- to 12 months post-CIC: 18 months base salary + 18 months COBRA reimbursement + lump sum 1.5x target bonus + full acceleration of time-based equity; performance awards per award terms; subject to release
280G Treatment“Better-of” reduction to avoid excise tax if it results in greater after-tax benefit (no tax gross-up)
ClawbackNot disclosed

Board Governance

  • Board service: Director since 2006; current Class III term expires in 2027 .
  • Committee roles: O’Connell is not a member of Audit, Compensation, or Nominating committees .
  • Independence: O’Connell is not independent; the board’s Chair (Sean Stalfort) is independent .
  • Board activity: Board met six times in 2024; each member attended ≥75% of meetings .
  • Director compensation framework (for non-employee directors): annual retainers and committee fees; 2025 amendment adds RSUs to annual director grants .

Compensation Structure Analysis

  • Shift toward equity mix: RSU grant-date value rose from $696,540 (2023) to $1,696,230 (2024), while option grant-date value decreased modestly from $2,190,177 to $2,036,867, increasing fixed equity elements (RSUs) versus options risk profile .
  • Incentive outcomes: 2024 corporate performance assessed at 119% resulting in a $406,768 bonus; the CEO’s incentive is 100% corporate-weighted, reinforcing alignment to centralized milestones rather than individual metrics .
  • Perquisites: Limited to de minimis items (cell phone, wellness, HSA, life insurance premium reimbursements, $25 gift cards with $1 tax gross-up) .
  • Consultant oversight: Aon engaged to set peer comparative frameworks and compensation recommendations; committee retains independent judgment .
  • No related party transactions disclosed outside standard compensation .

Equity Vesting & Potential Selling Pressure

AwardQuantityVesting CadenceKey Dates
RSU (2023)76,0001/3 annually1/17/2024, 1/17/2025 vested; final tranche 1/17/2026
RSU (2024)401,0001/3 annually1/2/2025 vested; remaining 1/2/2026 and 1/2/2027
Option (2024, $4.23)602,00048 monthly installmentsFully vests by 1/2/2028; expires 1/2/2034
Earlier Options (various)See ownership tableMonthly vest schedules2022 series completes 1/19/2026; 2023 series completes 1/17/2027; prior grants largely fully vested

Insider trading policy prohibits hedging and margin accounts, reducing forced selling risk from margin calls; no pledging is disclosed .

Director Compensation (for completeness)

  • O’Connell receives no separate director compensation; non-employee director fee schedule and annual equity are disclosed for others; board updated director equity mix in March 2025 .

Investment Implications

  • Alignment: 4.2% beneficial ownership and substantial unvested RSUs/options suggest long-dated alignment with program milestones; policy bans hedging/margin accounts, limiting misalignment risk .
  • Retention risk: Double-trigger CIC with 18 months salary, 1.5x bonus, and full acceleration of time-based equity reduces flight risk and protects continuity through strategic events .
  • Near-term supply/demand on stock: RSU tranches in January 2026 and January 2027 and continuous monthly option vesting through 2028 create periodic potential selling windows; monitor Form 4s around those dates for trading pressure signals .
  • Pay-for-performance: Cash bonuses tied to R&D and operational objectives (119% attainment in 2024) indicate internal milestone focus; absence of market-based metrics (e.g., TSR) in the incentive design may reduce direct linkage to shareholder returns in pre-commercial phases .
  • Governance quality: Independent chair and committee independence mitigate CEO dual-role concerns; no related-party transactions disclosed; director compensation policy modernized to include RSUs in 2025 .