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Jeffrey Ives

Director at Acumen Pharmaceuticals
Board

About Jeffrey L. Ives

Jeffrey L. Ives, Ph.D., age 74, has served as an independent director of Acumen Pharmaceuticals (ABOS) since May 2014. He is a neurosciences-focused executive and scientist: former CEO of Satori Pharmaceuticals (2008–2013), prior Senior Vice President at Pfizer leading global drug metabolism and neurodegenerative, psychiatry and pain research; he holds a Ph.D. and M.S. from Yale and a B.A. from Colgate University. The Board has affirmatively determined Dr. Ives is independent under Nasdaq standards.

Past Roles

OrganizationRoleTenureCommittees/Impact
Satori Pharmaceuticals, Inc.Chief Executive Officer2008–2013Led Alzheimer’s disease-focused company
Pfizer Inc.Senior Vice PresidentPrior to 2008 (years not specified)Led global drug metabolism and neurodegeneration/psychiatry/pain research areas

External Roles

OrganizationRoleTenurePublic/Private
Cara Therapeutics, Inc.DirectorSince 2014Public biopharmaceutical company
Astrocyte Pharmaceuticals, Inc.DirectorCurrentNot specified in proxy
Pinteon Therapeutics, Inc.DirectorPriorNot specified in proxy
Orthogonal Neuroscience LLCDirectorPriorNot specified in proxy
NeuroPharma Advisors, LLCPrincipalCurrentPrivate advisory
Access Biotechnology, Inc.AdvisorCurrentNot specified in proxy

Board Governance

CommitteeMemberChair2024 Meetings
AuditNo4
CompensationYesYes4
Nominating & Corporate GovernanceNo3
  • Board leadership: Independent Chair (Sean Stalfort) separates Chair/CEO roles to reinforce oversight independence.
  • Independence: The Board determined Dr. Ives (and a majority of directors) are independent under Nasdaq rules.
  • Attendance: The Board met six times in 2024; each director attended at least 75% of Board and committee meetings for which they served.
  • Risk oversight: Compensation Committee monitors compensation-related risk; Audit oversees financial reporting, internal control, and cybersecurity; Nominating oversees governance guidelines.

Fixed Compensation

Metric20242025 Policy/Update
Director annual cash retainer$40,000 (increased from $35,000 effective June 1, 2024) $40,000 (policy unchanged from 2024 increase)
Compensation Committee chair retainer$10,000 $10,000
Fees earned (cash) – Dr. Ives$47,917

Notes:

  • Committee member retainers (if applicable): Audit member $7,500; Compensation member $5,000; Nominating member $4,000; not applicable to Dr. Ives beyond chair role in Compensation for 2024.

Performance Compensation

Equity Component20242025 Policy/Update
Annual stock option award (continuing directors)25,000 options; vests at next annual meeting or one year 19,500 options per director
Annual RSU award (continuing directors)Not used in 2024 director program 12,800 RSUs per director
Option grant fair value (Dr. Ives)$49,855

Performance metric design:

  • Director equity awards vest on service-based schedules (time-based); no performance metrics disclosed for director equity (e.g., no TSR/EBITDA targets tied to director compensation).

Other Directorships & Interlocks

ItemDetail
Large shareholder linkage within Compensation CommitteeCompensation Committee members are Drapkin, Ives (Chair), and Stalfort; Stalfort is President of PBM Capital. Entities affiliated with Paul B. Manning (address c/o PBM Capital Group) own 5.3% of ABOS—potential perceived influence from an investor-affiliated director on pay decisions.
  • Related party transactions: None requiring disclosure since January 1, 2023 (other than executive/director compensation).

Expertise & Qualifications

  • Deep neurodegenerative disease expertise (Alzheimer’s), former CEO of Satori and senior R&D leadership at Pfizer.
  • Scientific and operational credentials: Ph.D./M.S. Yale; B.A. Colgate; leadership in drug metabolism and CNS research areas.
  • Governance experience: Long-tenured public company director (Cara Therapeutics since 2014).

Equity Ownership

Metric2024-12-312025-04-08 (Record Date)
Beneficial ownership (shares)87,802 (options exercisable within 60 days)
Beneficial ownership (% of outstanding)<1%
Options outstanding (aggregate)112,802

Notes:

  • The proxy footnote states Dr. Ives’ beneficial ownership consists entirely of options exercisable within 60 days of April 8, 2025 (no direct common shares disclosed).
  • Aggregate options held as of year-end for non-employee directors: Dr. Ives had 112,802.

Governance Assessment

  • Committee leadership: As Compensation Committee Chair, Dr. Ives oversees CEO/executive pay strategy, advisor selection (Aon), and risk review—role is central to pay-for-performance alignment.
  • Independence and attendance: Independent and met minimum attendance standards; Board structure includes independent Chair, supporting objective oversight.
  • Pay structure: 2024 director pay was balanced between cash ($47,917) and option equity ($49,855). 2025 policy adds RSUs, increasing ownership alignment and reducing option-only risk.
  • Ownership alignment: Beneficial ownership is exclusively near-term exercisable options per the record date footnote; 2025 RSUs should improve long-term equity hold expectations versus options alone.
  • Conflicts/related-party exposure: No related-person transactions disclosed; however, investor-affiliated director on Compensation Committee (Stalfort/PBM Capital) alongside a >5% holder linked to PBM could create perceived influence—mitigated by overall independence determinations and formal related-party review policies.
  • RED FLAGS: None disclosed regarding related-party transactions, pledging, or low attendance; monitor Compensation Committee composition and investor affiliations for perceived conflicts in pay decisions.

Consultant independence and process: The Compensation Committee engaged Aon to develop peer groups and compensation recommendations for executives and directors; the Committee considers advisor independence factors and retains full authority over fees/terms.