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Laura Stoppel

Director at Acumen Pharmaceuticals
Board

About Laura Stoppel

Independent director since November 2020; age 39 as of April 1, 2025. Partner on the Investment Team at RA Capital Management with prior roles at RA Capital since 2016, bringing venture investing and neuroscience domain expertise. Education: B.A. in Biology and Psychology (Harvard) and Ph.D. in Neuroscience (MIT). Board tenure: Class II director with term expiring in 2026.

Past Roles

OrganizationRoleTenureCommittees/Impact
RA Capital ManagementPartner, Investment Team; prior roles since 20162016–presentVenture investing focus; neurosciences specialization
Acumen Pharmaceuticals (ABOS)Independent Director (Class II)Nov 2020–present; term to 2026Audit Committee member; Nominating & Corporate Governance Committee chair

External Roles

OrganizationRoleTenurePublic/Private
Artiva Biotherapeutics, Inc.DirectorSince Jun 2020Public biotech
Nimbus Therapeutics, LLCDirectorSince Oct 2020Private LLC
Indapta Therapeutics Inc.DirectorSince Jan 2022Private
International Rett Syndrome FoundationDirectorSince Jul 2023Non-profit
CellCentric, Inc.DirectorSince Jul 2024Private
Verdiva Bio Inc.DirectorSince Oct 2024Private

Board Governance

  • Independence: Board affirmatively determined Dr. Stoppel is independent under Nasdaq rules.
  • Committee assignments: Audit Committee member; Nominating & Corporate Governance Committee chair; all committee members independent per Nasdaq.
  • Board leadership: Independent Chair (Sean Stalfort).
  • Attendance: Board met 6 times in FY2024; each director attended ≥75% of Board and applicable committee meetings; 2024 committee meetings—Audit (4), Compensation (4), Nominating (3).
CommitteeRoleFY2024 Meetings
AuditMember4
Nominating & Corporate GovernanceChair3

Fixed Compensation

YearCash Fees (Director Retainer + Committee Fees)Notes
2024$53,417Cash fees payable to Dr. Stoppel were paid to RA Capital Management, L.P. per her agreement.

Director cash fee policy (for context):

  • Board annual retainer increased to $40,000 effective June 1, 2024; Audit Chair $15,000; Audit member $7,500; Compensation Chair $10,000; Compensation member $5,000; Nominating Chair $8,000; Nominating member $4,000; Board Chair and Lead Independent Director each $30,000. Paid quarterly and pro-rated.

Performance Compensation

YearEquity Award TypeGrant SizeVestingGrant-Date Fair Value
2024Stock Option (annual director grant)25,000 optionsVest at earlier of 1 year or next annual meeting$49,855
OngoingInitial director grant (upon joining)50,000 options36 equal monthly installmentsn/a
2025 policy changeMixed equity19,500 options + 12,800 RSUsAs determined by Board/Comp Committeen/a
  • Director equity awards are time-based; no performance metrics (TSR/EBITDA/ESG) disclosed for director grants.

Other Directorships & Interlocks

  • Significant stockholder interlock: Entities affiliated with RA Capital beneficially own 15,016,063 shares (24.8%); disclosure notes 84,000 shares underlying options held by Dr. Stoppel for the benefit of RA Capital and excludes 25,000 unvested options not vesting within 60 days.
  • Cash flow to affiliated entity: Cash director fees payable to Dr. Stoppel were paid to RA Capital Management, L.P. pursuant to her agreement.

Expertise & Qualifications

  • Venture capital investor with neuroscience focus; current and prior roles at RA Capital since 2016.
  • Academic credentials: Harvard (B.A., Biology & Psychology) and MIT (Ph.D., Neuroscience).
  • Multiple board roles across biotech, foundation, and private companies; adds network reach and domain knowledge.

Equity Ownership

HolderForm of OwnershipShares/Units% of Outstanding
Laura Stoppel, Ph.D.Options exercisable within 60 days of Apr 8, 202584,000<1%
Laura Stoppel, Ph.D.Outstanding director options (as of Dec 31, 2024)109,000 underlying optionsn/a
RA Capital affiliated entitiesCommon stock + options for benefit15,016,063 (incl. 84,000 options for benefit; excludes 25,000 unvested)24.8%
  • Pledging/hedging: Company insider trading policy prohibits short sales, options, hedging, margin accounts, and speculative transactions by directors. No pledging disclosed.
  • Stock ownership guidelines for directors: Not disclosed in proxy materials. (No statement in provided sections; equity program described without guidelines.)

Governance Assessment

  • Strengths: Independent status; chairs Nominating & Corporate Governance and sits on Audit—key governance/compliance oversight; met ≥75% attendance threshold; Board led by independent Chair. These factors support board effectiveness and investor confidence.
  • Alignment: Director equity compensation historically option-based with time-based vesting; 2025 shift adds RSUs, increasing guaranteed value and potentially lowering risk sensitivity, but remains standard for small-cap biotech boards.
  • Conflicts/Interlocks—RED FLAGS: RA Capital is a 24.8% holder; Dr. Stoppel is an RA Capital partner, and her cash director fees are paid to RA Capital. This creates a material interlock and potential perceived conflict, particularly given her chair role on Nominating & Corporate Governance. Mitigants: Board independence affirmed; Related party transactions policy in place; Company disclosed no related-party transactions (other than compensation) since Jan 1, 2023.
  • Engagement: Committee workload evident (Audit 4; Nominating 3 meetings in FY2024) suggesting active oversight cadence.

Overall, governance quality appears solid (independence, committee leadership, attendance), but investors should monitor RA Capital interlock dynamics and the 2025 equity mix change for directors (introduction of RSUs) as potential signals regarding risk/return alignment and control influence.