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James M. Daly

Director at ACADIA PHARMACEUTICALSACADIA PHARMACEUTICALS
Board

About James M. Daly

Independent director at Acadia Pharmaceuticals since January 2016; age 63. Former Executive Vice President and Chief Commercial Officer at Incyte and senior commercial leader at Amgen and GlaxoSmithKline, with a track record of launching major biologics. Education: B.S. in Pharmacy and MBA, University at Buffalo (SUNY). Currently serves on public company boards Argenx SE and Madrigal Pharmaceuticals, bringing deep commercial biopharma expertise to ACAD’s board .

Past Roles

OrganizationRoleTenure/TimingCommittees/Impact
Incyte CorporationExecutive Vice President & Chief Commercial OfficerOct 2012–Jun 2015Led commercial function .
Amgen, Inc.Senior Vice President, North America Commercial Operations; Global Marketing & Commercial Development; VP & GM Oncology10 years (prior to Incyte)Led successful launches: Aranesp, Neulasta, Vectibix, Nplate, Xgeva, Prolia .
Glaxo Wellcome/GlaxoSmithKlineSenior Vice President, GM Respiratory & Anti-Infective16+ yearsLed U.S. launch of Advair .

External Roles

CompanyRoleStatusNotes
Argenx SEDirectorCurrentPublic company board .
Madrigal Pharmaceuticals, Inc.DirectorCurrentPublic company board .
Chimerix Inc.DirectorPrior (past 5 years)Public company .
Bellicum Pharmaceuticals, Inc.DirectorPrior (past 5 years)Public company .
Halozyme Therapeutics, Inc.DirectorPrior (past 5 years)Public company .

Board Governance

  • Independence: Board affirmatively determined all current directors are independent except the CEO; Daly is independent under Nasdaq rules .
  • Committee memberships (2024): Audit Committee member; Compensation Committee member; not a chair .
  • Formal committee reports: Listed on the Audit Committee report; listed on the Compensation Committee report .
  • Board leadership: Independent, non-executive Chair separates oversight from management .
  • Executive sessions: Independent directors meet at least quarterly in executive session .
  • Attendance: Board met 16 times in 2024; all directors attended at least 75% of Board and committee meetings .

Fixed Compensation

Director cash compensation program (2024):

ElementAmount (USD)
Annual Board retainer$50,000
Board Chair retainer$30,000
Audit Chair$20,000
Audit Member (non-Chair)$10,000
Compensation Chair$20,000
Compensation Member (non-Chair)$10,000
Nominating & Corporate Governance Chair$10,000
Nominating & Corporate Governance Member$5,000
Scientific Advisory Committee Chair$20,000
Scientific Advisory Committee Member$10,000

Daly’s 2024 cash fees and equity grant values (as reported):

ItemAmountNotes
Fees Earned or Paid in Cash$122,083Includes Board retainer and applicable committee retainers .
Option Awards (grant date fair value)$138,89415,959 options granted 5/29/2024 at $14.62 strike .
Stock Awards (RSUs grant date fair value)$137,2389,387 RSUs granted 5/29/2024 .

Performance Compensation

Director equity award structure (ongoing program):

ComponentTarget Fair ValueVesting
Annual Stock Options$150,000Quarterly over 1 year; final tranche vests at 1 year or next annual meeting .
Annual RSUs$150,000Vest in full at 1 year or next annual meeting .
New Director Inducement (Options)$150,000Equal annual installments over 2 years .
New Director Inducement (RSUs)$150,000Equal annual installments over 2 years .

2024 Daly grants and vesting specifics:

  • Options: 15,959 at $14.62 granted on May 29, 2024; standard director vesting applies .
  • RSUs: 9,387 granted on May 29, 2024; standard director vesting applies .

Note: ACAD’s director equity compensation is time-based (no TSR/operational metrics), aligning directors with shareholder outcomes via equity ownership rather than formulaic performance metrics .

Other Directorships & Interlocks

  • Compensation Committee Interlocks: ACAD discloses the committee consists of Biggar (Chair), Daly, and Garofalo; no member has ever been an ACAD officer/employee; no interlocks involving ACAD executives at other companies’ compensation committees .
  • Related-party transactions: The proxy includes ACAD’s related-person transaction policy and process; no related-person transactions involving Daly are disclosed in the 2025 proxy .

Expertise & Qualifications

  • Deep commercial biopharma leadership (Incyte, Amgen, GSK) with multiple blockbuster launches; strong strategic marketing and P&L oversight credentials .
  • Pharmacy background (B.S.) and MBA supports domain and managerial rigor .
  • Current public company board experience (Argenx, Madrigal) enhances governance and market perspective .

Equity Ownership

Beneficial ownership as of February 15, 2025 (Measurement Date):

HolderShares Owned DirectlyOptions Exercisable within 60 daysTotal Beneficial Ownership% of Shares Outstanding
James M. Daly24,654108,348133,002<1% (outstanding shares: 166,788,517) .
  • Outstanding director awards as of 12/31/2024 for Daly: aggregate 112,338 options and 9,387 RSUs (cumulative granted/vested status per table footnotes) .
  • Hedging/pledging: Prohibited for directors and designated insiders under ACAD’s Insider Trading Policy .
  • Director stock ownership guidelines: 5x regular annual cash retainer ($250,000 equivalent); counts owned shares and unvested time-based RSUs; 50% retention until met; compliance status across non-employee directors is in compliance or within allowed timeframe .

Governance Assessment

  • Board effectiveness: Daly is an active member of both Audit and Compensation Committees, contributing to financial oversight, pay governance, and risk monitoring (including cybersecurity oversight within Audit broadly) .
  • Independence & engagement: Affirmed independent; formal participation in committee reports; attendance threshold met; quarterly executive sessions support independent oversight .
  • Alignment: Director compensation mix balances cash retainers with equity (options and RSUs) that vest on service, reinforcing shareholder alignment without incentivizing short-term metrics; RSUs count toward ownership guidelines; hedging/pledging prohibitions strengthen alignment .
  • Conflicts and related-party exposure: No related-person transactions involving Daly disclosed; ACAD’s policy requires Audit Committee review and recusal for any such matters, mitigating conflict risk .
  • RED FLAGS: None disclosed specific to Daly—no hedging/pledging, no related-party transactions, and independence affirmed; multiple external directorships noted but no interlocks or attendance issues reported .