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Lauren D’Angelo

Chief Operating Officer at Alpha Cognition
Executive

About Lauren D’Angelo

Lauren D’Angelo is 46 and serves as Chief Operating Officer (COO) since 2023; she joined Alpha Cognition as Chief Commercial Officer (CCO) on May 4, 2021 and was promoted to COO as of September 28, 2023 . She has 20+ years of CNS and specialty commercial leadership, previously VP, Marketing & Commercial Strategy at Urovant Sciences (Oct 2017–May 2021), and holds a B.S. in MIS (Florida State University) and an MBA (University of Florida) . Notable recognitions include 2023 PharmaVoice Top 100 Industry Leader, MM+M 2022 Woman of Distinction, MM+M 2017 Woman to Watch, and Pharmaceutical Executive’s 2020 Emerging Pharma Leader . Company milestones during her tenure include FDA approval of ZUNVEYL (ALPHA-1062) on July 29, 2024, enabling U.S. commercialization in mild-to-moderate Alzheimer’s disease . Specific TSR, revenue growth, and EBITDA growth targets tied to her pay were not disclosed .

Past Roles

OrganizationRoleYearsStrategic Impact
Urovant Sciences, Inc.VP, Marketing & Commercial StrategyOct 2017 – May 2021Led marketing and commercial strategy; CNS commercialization experience

External Roles

OrganizationRoleYearsStrategic Impact
No public company directorships or external board roles disclosed

Fixed Compensation

MetricFY 2022FY 2023FY 2024
Base Salary ($)$359,712 $410,099 $420,000
Target Bonus (% of Base)50% (contract term) 50% (contract term) 50% (contract term)
Actual Cash Bonus ($)$195,350 $89,928 $209,151
Healthcare/Other ($)$25,551 $30,186 $31,186

2025 adjustments approved by the Compensation Committee:

  • Base salary increased to $500,000 (effective Feb 18, 2025) .
  • 2025 target cash bonus set at $300,000 .
2025 Compensation TargetsValue
Base Salary ($)$500,000
Target Bonus ($)$300,000
Option Compensation ($ FV)$1,500,000

Performance Compensation

ComponentMetricWeightingTargetActual/PayoutVesting
Annual Cash BonusCriteria set by CEO, approved by BoardNot disclosed 50% of base $209,151 (2024) Annual; not disclosed beyond cash timing
Bonus Rights (Cash-Settled)FMV of share – $39.50, × vested rightsNot applicableUp to 42,258 rights (granted May 2022) 29,505 rights earned as of Mar 31, 2025 ; carrying value $31,177 (Mar 31, 2025), $52,893 (Jun 30, 2025), $44,729 (Sep 30, 2025) Vests over time per plan; accounted in other liabilities
Stock Options (2023 grants)Time-basedNot disclosed158,000 options (Jun 8, 2023) Option awards FV $684,184 (2023) 12.5% vest at grant (Jun 8, 2023), remainder monthly until Jan 30, 2026
Option Regrants (Jan 2023)Time-basedNot disclosed24,000 + 6,000 regranted at $7.00 Included in 2023 option awards Equal monthly installments until Jul 31, 2024; expiries unchanged

Outstanding equity awards (as of Dec 31, 2024):

Grant DateExercisable (#)Unexercisable (#)Exercise Price ($)Expiration
Jan 18, 2023 (ISO)19,999 4,000 $5.25 Jan 18, 2033
Feb 14, 2023 (ISO)3,750 2,250 $5.25 Feb 14, 2033
Jun 8, 2023 (NQSO)41,236 55,374 $4.25 Jun 8, 2033
Jun 8, 2023 (ISO)26,037 35,353 $4.25 Jun 8, 2033

Notes:

  • 2023 option awards include cancellations and reissues at lower strikes (repricing/modification) with new vesting terms; expiries unchanged . The 2025 Stock & Incentive Plan prohibits repricing without shareholder approval going forward .

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership318,250 (includes shares underlying vested options exercisable within 60 days)
% of Common Shares1.9%
% of Total Voting Stock1.8%
Vested vs Unvested318,250 vested options; 299,779 unvested options excluded from beneficial ownership
Pledging/HedgingCompany policy prohibits hedging/monetization transactions (e.g., collars, exchange funds) for directors/officers; no pledging by Ms. D’Angelo is disclosed in the proxy .
Ownership GuidelinesNo explicit officer stock ownership guidelines disclosed .
Lock-upIdentified as a lock-up party in the Sept 2025 offering Underwriting Agreement; subject to lock-up terms during offering period .

Employment Terms

TermProvision
Role & StartCCO effective May 4, 2021; promoted to COO Sept 28, 2023
Base SalaryInitially $420,000; increased to $500,000 on Feb 18, 2025
Target Bonus50% of base salary; 2025 target bonus set at $300,000
Equity EligibilityEligible for options under Company plans
TerminationAgreement may be terminated by either party at any time, with/without advance notice
Change-of-Control (COC)Cash payment equal to annual base salary; full bonus payable in cash immediately (irrespective of targets); continuation of healthcare benefits for 12 months
ClawbackExecutive Incentive Compensation Recovery Policy effective Nov 12, 2024, mandatory recovery of erroneously awarded incentive compensation upon accounting restatement (3-year lookback) per SEC/Nasdaq rules
Insider TradingTrading policy with blackout periods; approvals required for certain officers/directors

Compensation Structure Analysis

  • Shift toward equity in 2023: Option awards peaked at $684,184 in 2023, with significant time-based grants and regrants at reduced strikes; 2024 emphasized cash bonus ($209,151) amid commercialization ramp .
  • Repricing/modification: 2023 cancellations and reissuance of options at lower exercise prices with new vesting terms are a governance flag; the 2025 plan now restricts future repricing without shareholder approval .
  • At-risk pay: Bonus tied to CEO/Board-set criteria (not formulaically disclosed); presence of cash-settled bonus rights linked to stock price above $39.50 adds performance sensitivity but has carried modest liabilities as of 2025 dates .

Performance & Track Record

  • Commercial execution: Company received FDA approval for ZUNVEYL on July 29, 2024, enabling commercialization; Ms. D’Angelo leads commercial and operations functions supporting launch .
  • CFO transition: Prior CFO resigned Oct 1, 2024; interim CFO appointed Oct 21, 2024; operational continuity maintained but executive turnover is a general execution risk consideration .

Equity Ownership & Vesting Schedules (Detail)

DateEarned Bonus Rights (#)Carrying Value ($)
Dec 31, 202429,505$28,196
Mar 31, 202529,505$31,177
Jun 30, 202529,505$52,893
Sep 30, 202529,505$44,729

Option vesting highlights:

  • Jun 8, 2023 grants: 12.5% immediate vest, remaining 87.5% vest monthly to Jan 30, 2026 .
  • Jan 2023 regrants: monthly vest to Jul 31, 2024; expirations unchanged .

Board Governance and Compensation Committee (Context)

  • Compensation Committee: Phillip Mertz (Chair), Rajeev “Rob” Bakshi; both independent under Nasdaq rules .
  • New 2025 Stock & Incentive Plan: Fixed 2,000,000 share pool; prohibits repricing; awards subject to clawback; non-evergreen design .

Investment Implications

  • Pay-for-performance alignment: Cash-settled bonus rights linked to share price and substantial time-based option grants create market-linked upside, but lack of disclosed operational KPIs for annual bonus reduces transparency on incentive quality .
  • Selling pressure: Inclusion in the Sept 2025 lock-up reduces near-term selling risk; outstanding unvested options through Jan 2026 point to continued retention incentives .
  • Governance flags: 2023 option regranting at lower strikes is a red flag; mitigated by the 2025 plan’s ban on repricing without shareholder approval and adoption of a compliant clawback policy .
  • Ownership alignment: 1.8% total voting power via vested options and 1.9% of common shares provides meaningful alignment, with no pledging disclosed and hedging prohibited, supporting shareholder alignment .