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Mary-Alice Miller

Chief Legal Officer at Acrivon Therapeutics
Executive

About Mary-Alice Miller

Mary-Alice Miller, J.D., is Acrivon Therapeutics’ Chief Legal Officer (since September 2023), after serving as General Counsel from October 2022 to September 2023; she has also been Corporate Secretary since December 2022 . She holds a B.A. and a J.D. from Boston College and has 20+ years of corporate legal experience, including serving as general counsel of two companies taken public (per company investor materials) . Prior roles include General Counsel at Butterfly Network (Dec 2020–Jun 2022) and General Counsel and Chief Risk Officer at Columbia Care (Dec 2017–Dec 2020), as well as a stint at Outside GC (Mar–Dec 2017) . In 2023 she was a named executive officer, reflecting her executive-level compensation and governance responsibilities during that year .

Past Roles

OrganizationRoleYearsStrategic impact
Butterfly Network, Inc.General CounselDec 2020 – Jun 2022Public-company GC role in digital health; part of executive legal leadership .
Columbia CareGeneral Counsel and Chief Risk OfficerDec 2017 – Dec 2020Enterprise legal/risk leadership at a medical cannabis company .
Outside GCMember (outside counsel)Mar 2017 – Dec 2017Provided outsourced general counsel support to client companies .

External Roles

  • No public-company directorships or external board roles are disclosed for Ms. Miller in Acrivon’s executive officer biographies or governance disclosures .

Fixed Compensation

  • Base salary and target bonus history (offer letter and amendments)
Effective dateBase salary ($)Target bonus (% of salary)Source
Mar 16, 2023416,00040%Board-approved increase from $400,000 in March 2023 .
Sep 12, 2023 (promotion to CLO)435,00040%Offer letter amended on promotion to CLO .
  • 2023 named executive compensation (actuals)
Metric2023
Salary ($)418,501
Stock awards grant-date fair value ($)34,529
Option awards grant-date fair value ($)75,366
Non-equity incentive plan compensation ($)168,607
Total ($)697,003

Notes:

  • For 2023, Acrivon’s Board determined corporate performance goals were achieved at 100%, supporting cash incentive payouts; Ms. Miller’s target bonus was 40% of base salary .

Performance Compensation

  • Annual cash incentive design and 2023 payout
MetricWeightingTargetActualPayout basisVesting
Annual cash bonus (2023)Not disclosed40% of base salary$168,607Corporate goals achieved at 100% for 2023 (plus individual objectives) Cash (not applicable)
  • Equity incentives and vesting practice (company-standard)
    • Company equity awards include stock options and RSUs; options granted post-IPO typically vest 25% on the one-year anniversary with the remainder vesting in 36 equal monthly installments; RSUs often vest 25% after one year then in equal quarterly installments thereafter, subject to continued service .
    • Ms. Miller received equity in 2023 (RSUs and options) and was among officers who filed a late Form 4 related to an option grant dated March 1, 2024 (administrative oversight), evidencing continued equity participation; award counts for Ms. Miller are not itemized in the proxy .

Equity Ownership & Alignment

  • Beneficial ownership: Ms. Miller is not individually itemized in the April 21, 2025 beneficial ownership table (which lists 5% holders, directors, and named executive officers); as such, her total beneficial ownership and pledged shares (if any) are not disclosed in that table .
  • Company insider trading policy and governance: Acrivon maintains an Insider Trading Policy applicable to employees, officers, directors, and consultants; the policy is filed as an exhibit to the 2024 Form 10-K .
  • Stock ownership guidelines: Not disclosed for executives in the cited filings .

Employment Terms

  • Offer letter and severance/change-in-control terms (as amended at promotion)
    • Base salary and annual target bonus percentage are set by the Compensation Committee and may be adjusted over time .
    • Severance (non-change in control): if terminated without cause or resigns for good reason (outside the 12-month post-change-of-control window), cash severance equals six months of base salary, subject to a release .
    • Change-of-control (within 12 months post-CoC): if terminated without cause or resigns for good reason, cash severance equals six months of base salary plus full acceleration of all outstanding time-based equity awards, subject to a release (double-trigger) .
    • Clawback policy: The Compensation Committee is responsible for developing and implementing policies with respect to recovery of excess incentive-based compensation paid to officers based on erroneous data .

Risk Indicators & Red Flags

  • Section 16(a) filing timeliness: The company disclosed that multiple insiders, including “Mary Miller,” filed late Forms 4 on November 27, 2024 to report March 1, 2024 option grants due to an administrative oversight (process issue; not a misconduct finding) .
  • Hedging/pledging: No pledging or hedging by Ms. Miller is disclosed; the company cites its Insider Trading Policy and governance framework .
  • Related party transactions: None identified involving Ms. Miller in the related-person transactions section for 2023–2024 .

Governance & Responsibilities

  • Corporate Secretary: Ms. Miller serves as Corporate Secretary, reflecting a central role in governance processes and the annual meeting/proxy workflow; she is also named as a proxy holder on the 2025 proxy card .

Compensation Structure Analysis

  • Cash vs equity mix (2023): Ms. Miller’s 2023 compensation combined salary ($418.5k), a performance-based cash bonus ($168.6k), and modest equity grants (options and RSUs), indicating a balanced mix with meaningful at-risk components aligned to corporate performance achievement .
  • Shift in guaranteed vs at-risk: Her March and September 2023 base salary increases (to $416k and then $435k) reflect role elevation to CLO, while incentive eligibility remained at 40% of salary; equity participation continued via 2023 awards and a 2024 option grant (filing noted), maintaining pay-at-risk exposure .
  • Clawback controls: Committee-level mandate to implement clawbacks for excess incentive-based compensation supports pay-for-performance risk management .

Performance & Track Record

  • Tenure and scope: GC (Oct 2022–Sep 2023), CLO (Sep 2023–present), Corporate Secretary (since Dec 2022); portfolio spans SEC compliance, governance, and enterprise legal risk .
  • Company operating backdrop: As a clinical-stage biotech, Acrivon reported operating losses consistent with R&D-stage development (e.g., net loss of $58.9M for the nine months ended Sept 30, 2025), underscoring the importance of legal and regulatory execution during financing and clinical milestones .
  • Investor-facing role: Ms. Miller is named on the proxy card as a proxy holder for the 2025 annual meeting, indicating frontline governance engagement .

Performance Compensation Detail (Plan Mechanics)

ElementMetricTargetActual/PayoutNotes
Annual cash bonus (2023)Corporate and individual goals40% of salary$168,607 paidCorporate goals achieved at 100% in 2023 per proxy; individual weighting not disclosed .
Stock optionsService-vestedStandard scheduleGranted in 2023; additional grant dated Mar 1, 2024 (late Form 4)Post-IPO standard vest: 25% at one year, remaining monthly over 36 months (company practice) .
RSUsService-vestedStandard scheduleGranted in 2023Standard RSU vesting often 25% at one year then quarterly thereafter (company practice) .

Investment Implications

  • Alignment and retention: Double-trigger change-in-control economics with six months’ cash and full acceleration of time-based equity promote retention while preventing single-trigger windfalls; target bonus at 40% and continued equity participation maintain at-risk alignment .
  • Selling pressure/vesting cadence: Company-standard vesting (25% one-year cliff, then monthly/quarterly) and the March 1, 2024 option grant imply potential periodic supply as awards vest; exact share counts for Ms. Miller are not disclosed, tempering precision on projected selling pressure .
  • Governance quality: Presence of an insider trading policy, committee-level clawback mandate, and professionalized secretary/proxy processes support governance hygiene; the isolated late Form 4s indicate an administrative lapse rather than a systemic control failure based on current disclosures .

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