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Aaron Fletcher

Chairperson and Director at ACTUATE THERAPEUTICS
Board

About Aaron G.L. Fletcher, Ph.D.

Aaron Fletcher (age 44) is Chairperson of the Board and an independent director at Actuate Therapeutics, Inc. (ACTU) since April 2015; he holds a Ph.D. in Biochemistry (Colorado State University) and has deep healthcare/biotech investment and board experience . He is classified as a Class II director (term expires at the 2026 annual meeting) and the Board has determined he is independent under Nasdaq rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Bios ResearchFounder & PresidentSince 2012Healthcare/biotech equity research leadership
Independent ConsultantBiotechnology & healthcare equity consultant>10 yearsSector-focused advisory
Dallas Baptist UniversityVisiting Professor (Biochemistry, Bioethics, Cell Biology)Since 2008Academic teaching

External Roles

OrganizationRoleTenureCommittees/Impact
Cognition Therapeutics, Inc. (public)Director; Compensation Committee memberSince Jul 2015Compensation oversight
ONL Therapeutics, Inc. (private)DirectorSince Sep 2024Private biotech governance
TFF Pharmaceuticals, Inc. (public)Director; Compensation; Nominating & GovernanceMar 2018–Nov 2023Human capital & governance oversight
Cue Biopharma (public)Director; Compensation; Pricing CommitteeOct 2019–Oct 2023Pricing strategy; compensation
Rein Therapeutics (fka Aileron Therapeutics, Inc.) (public)Director; CompensationAug 2014–Oct 2023Compensation oversight
Lung Therapeutics, Inc. (biopharma)Director; CompensationAug 2014–Oct 2023Compensation oversight
AbiliTech Medical, Inc.Director; CompensationNov 2016–Jan 2023Compensation oversight
SWK Holdings Corporation (public)Director; Audit Committee memberAug 2019–Dec 2021Audit oversight

Board Governance

  • Structure and roles: Fletcher is Chairperson of the Board and chairs the Nominating & Corporate Governance Committee; the Board does not have a Lead Independent Director and independent directors meet in executive session regularly .
  • Committee memberships: Nominating & Corporate Governance Committee (Fletcher—Chair), with Todd Thomson and Dan Zabrowski; Audit Committee (Keyes—Chair, Ronneberg, Sawhney); Compensation Committee (Zabrowski—Chair, Ronneberg, Sawhney) .
  • Attendance and engagement: The Board met 5 times in 2024 and all directors attended at least 75% of Board and applicable committee meetings; the Nominating & Corporate Governance Committee held zero meetings in 2024 .
  • Independence: The Board determined Fletcher is independent under Nasdaq rules .
  • Classified board: Fletcher is a Class II director; Class II terms expire at the 2026 annual meeting .

Fixed Compensation

ComponentAmountNotes
Fees earned or paid in cash (2024)$29,971 Partial-year post-IPO; reflects program adoption in Aug 2024
Annual cash retainer – Chair of the Board$70,000 In lieu of $40,000 director retainer
Committee chair/member cash feesAudit Chair $19,000; Comp Chair $12,000; NCG Chair $8,000; Audit member $9,000; Comp member $6,500; NCG member $4,000 Program level; annualized post-IPO
  • Cash vs. equity mix (reported 2024): Cash $29,971 vs. option award fair value $94,335 → equity ~76% of reported director compensation .

Performance Compensation

Equity AwardGrant DateSharesExercise PriceVesting ScheduleReported Fair Value
Annual director option grantAug 12, 202415,000 $8.00/share Vests in full on 1st anniversary of grant for annual grants $94,335 (ASC 718)
  • Initial/annual grant policy: Initial grant 30,000 options at appointment; annual grants 15,000 options thereafter; initial grants vest in three equal annual installments; annual grants vest in full on the first anniversary .
  • MNPI timing policy: Awards are not timed around material nonpublic information; equity award policy governs timing .

Performance metrics tied to director compensation

MetricUsageTarget/WeightingDisclosure
Financial/operational metrics (e.g., revenue growth, TSR)Not used for director payN/ANot disclosed; director equity awards are time-based

Other Directorships & Interlocks

  • Affiliate control: Fletcher is Co-Founder/manager of Bios Capital Management LP and related entities that control Bios Equity Affiliated Funds; he and former director Les Kreis share voting/investment control over these funds .
  • Fund interlocks: Bios Equity Affiliated Funds participated in multiple ACTU financings (Series A/B/C preferred, warrants, bridge notes) and purchased 500,000 shares in the IPO; Kairos Venture Affiliated Funds (where director Todd Thomson is an officer) also participated in financings—potential information-flow interlocks across the Board via affiliated investors .
  • Related party governance: Audit Committee reviews and approves related-party transactions; formal policy requires recusal and arm’s-length assessment .

Expertise & Qualifications

  • Education: Ph.D. in Biochemistry (Colorado State University) .
  • Sector expertise: Extensive healthcare/biotech investment and board oversight across public and private companies (compensation, audit, pricing committees) .
  • Board leadership: Chairperson of ACTU Board; Chair of Nominating & Corporate Governance Committee .

Equity Ownership

HolderShares Beneficially Owned% of Outstanding
Aaron G.L. Fletcher (total)10,125,488 51.66%
Through Bios Equity Affiliated Funds10,048,403 51.26%
Direct and family trusts (personal)77,085 (60,973 direct; 8,056 KF Legacy Trust; 8,056 MF Legacy Trust) 0.39%
  • Ownership guidelines: Not disclosed for directors .
  • Hedging/pledging: Insider trading policy prohibits short sales, derivatives/hedging, margining, and pledging company stock as collateral (mitigates pledge risk) .

Governance Assessment

  • Alignment vs. control: Fletcher’s substantial beneficial ownership (>50%) strongly aligns incentives with shareholders but concentrates control and may influence Board dynamics, including director elections and strategic decisions .
  • Independence optics: While the Board determined Fletcher is independent under Nasdaq rules, his leadership role at Bios-affiliated funds that repeatedly financed ACTU (convertible preferred, warrants, bridge notes, IPO purchase) creates perceived conflicts; the company maintains a formal related-party policy and Audit Committee approval processes, but investor scrutiny is warranted .
  • Committee effectiveness: The Nominating & Corporate Governance Committee (chaired by Fletcher) held zero meetings in 2024 despite IPO transition and board refresh—this is a governance engagement concern; Audit and Compensation Committees met and have independent chairs and defined charters .
  • Attendance: Board attendance (≥75% for all directors) is adequate; the Board held 5 meetings in 2024 .
  • Policies: A clawback policy compliant with Nasdaq and an insider trading policy banning hedging/pledging are positives .
  • Board structure: No Lead Independent Director; independent directors meet in executive session regularly—ongoing best-practice evaluation recommended given concentrated ownership .

RED FLAGS

  • Controlling beneficial ownership by Fletcher/Bios-affiliated funds (51.66%) may impair perceived independence and raise minority shareholder protection concerns .
  • Extensive related-party financing history (preferred rounds, bridge notes, IPO participation) demands rigorous oversight and transparent recusal procedures .
  • Nominating & Corporate Governance Committee held zero meetings in 2024 despite material governance changes (IPO, board expansion)—questionable committee engagement .

Positive Signals

  • Clear related-party transaction policy and Audit Committee oversight; independent committee composition; clawback policy; prohibition on hedging/pledging .