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Keyvan Mirsaeedi-Farahani

Director at Adagio Medical Holdings
Board

About Keyvan Mirsaeedi-Farahani

Independent Class III director at Adagio Medical Holdings, Inc. (ADGM) since August 2024; age 38. Managing Director at Perceptive Advisors (focus on early/late stage therapeutics and early-stage medical devices). Education: MD (Perelman School of Medicine, University of Pennsylvania), MBA (Harvard Business School), dual BS/BBA (University of Michigan). Board independence affirmed under Nasdaq standards; serves as Chair of the Nominating & Corporate Governance Committee; Board met five times in the last fiscal year and each director attended at least 75% of meetings held for the period served .

Past Roles

OrganizationRoleTenureCommittees/Impact
Perceptive AdvisorsManaging Director (investment team)2016–presentFocus on early/late stage therapeutics, early-stage medical devices
McKinsey & CompanyBusiness Analyst2009–2011Strategy/analytics experience

External Roles

OrganizationRoleTenureNotes
Perceptive AdvisorsManaging Director2016–presentPerceptive-affiliated entities are ADGM’s largest holders (see Interlocks)
Public company directorshipsNone disclosed in ADGM’s proxy

Board Governance

  • Committee assignments and chair roles (current): Chair, Nominating & Corporate Governance Committee; not listed as a member of Audit or Compensation Committees .
  • Independence: Board affirmatively determined he is independent under Nasdaq rules; Board noted certain relationships reviewed did not impair independence .
  • Attendance and engagement: Board met five times in the last fiscal year; each director attended ≥75% of Board and applicable committee meetings for their service period. The Nominating & Corporate Governance Committee showed “—” meetings in fiscal 2024 (committee structure established post-Business Combination) .
  • Committee scope (Nominating & Corporate Governance): Oversees director qualifications/selection, Board/committee composition, CEO and executive succession process, director orientation/education, ESG programs/disclosures, Board/committee performance evaluations, and shareholder communications policy .

Fixed Compensation

ComponentPolicy Detail (2025 program)Keyvan’s 2024 Actual
Annual cash retainer (non-employee directors)$40,000 per year, paid quarterly in arrears; prorated for partial service periods $12,500 (cash fees for service from Jul 31–Dec 31, 2024)
Committee chair retainersAudit $20,000; Compensation $13,000; Nominating & Corporate Governance $10,000 (annual) Included in the prorated 2024 amount, with program applied post-closing and paid in 2025
Committee member retainers (non-chair)Audit $10,000; Compensation $7,000; Nominating & Corporate Governance $5,000 (annual) N/A for 2024 disclosure (aggregate shown above)
Meeting feesNone disclosed (retainers only)

Notes: Non-employee director fees for 2024 were paid in 2025 and prorated from the Business Combination closing date (July 31, 2024) to year-end. Directors are reimbursed for ordinary Board-related expenses .

Performance Compensation

InstrumentGrant BasisGrant SizeVestingPricing/ExerciseStatus/Notes
Initial stock option (non-chair directors)Upon first appointment; adopted Mar 2025 with vesting service credit from Jul 31, 202490,000 options (policy) Equal monthly installments over 3 years, service-based Exercise price = FMV on grant date; options exercisable during service and for one year post-service; 10-year max term Company granted initial options to then-current non-employee directors in Mar 2025 under this policy
Annual stock option (non-chair directors)Each annual meeting while serving30,000 options (policy) Equal monthly installments over 1 year, service-based FMV on date of grant; standard terms Ongoing while serving
  • Director equity plan caps: Non-employee director total compensation (cash + equity grant-date value) capped at $750,000 per fiscal year ($1,000,000 in initial year) under the 2024 Equity Incentive Plan .
  • Clawback: Company maintains an incentive compensation clawback policy compliant with SEC/Nasdaq rules (executives covered). Director equity is service-based; no director-specific clawback provided in proxy .
  • Hedging/pledging: Insider Trading Policy prohibits short sales, options, hedging transactions, margin accounts for non-employee directors, enhancing alignment with shareholders .

Other Directorships & Interlocks

RelationshipDetailGovernance/Conflict Consideration
Perceptive Advisors affiliationKeyvan is a Managing Director at Perceptive Advisors Perceptive-affiliated entities are the largest holders of ADGM; Board has reviewed relationships and affirmed independence
Largest shareholder position (Perceptive affiliates)57.55% beneficial ownership including 9,675,684 shares, 5,445,069 warrants, and 200,902 shares via C2 (beneficial calc as of Oct 24, 2025; certain additional pre-funded/milestone warrants excluded due to 9.99% blocker) Potential influence over governance/strategic direction; Board independence determination stands; related party policy in place
2025 PIPE participation (Perceptive affiliates)Purchased pre-funded warrants for 2,190,496 shares and 4,034,997 milestone warrants; ~$4.25M aggregate purchase price Related party capital support; transaction subject to related-party review policy

Expertise & Qualifications

  • Investment and healthcare focus: Managing Director at Perceptive Advisors with focus on therapeutics and medical devices; prior strategy experience at McKinsey .
  • Education: MD (Penn), MBA (Harvard), BS/BBA (Michigan) .
  • Board skills emphasis: Operational/transactional experience cited by the Board as rationale for his appointment .

Equity Ownership

HolderCommon SharesOptions Exercisable within 60 DaysTotal Beneficial Ownership% Outstanding
Keyvan Mirsaeedi-Farahani12,770 40,000 52,770 <1% (asterisked in table)

Notes: Beneficial ownership percentages based on 21,179,637 shares outstanding as of Oct 24, 2025. Only options exercisable within 60 days are included per SEC rules; additional unvested options, if any, are excluded .

Governance Assessment

  • Strengths

    • Independent director; Chair of Nominating & Corporate Governance Committee overseeing director pipeline, ESG, and Board evaluations; Board reports ≥75% attendance for all directors in the last fiscal year .
    • Clear, market-standard non-employee director compensation program with modest cash retainers and time-based equity; prohibitions on hedging/pledging enhance alignment .
  • Potential Risks and RED FLAGS

    • Majority shareholder representation: As a Managing Director at Perceptive Advisors while Perceptive affiliates beneficially own 57.55% and participated in the 2025 PIPE, there is an inherent perceived conflict. The Board affirmed independence and has a related-party transactions policy; investors should monitor NCG decisions (board composition/succession) given his chair role. RED FLAG: controlling holder nexus with committee leadership .
    • Audit Committee non-compliance: Company disclosed non-compliance with Nasdaq’s audit committee requirements while evaluating options, indicating broader Board governance risk, though not specific to Keyvan’s committee. RED FLAG: exchange compliance gap .
    • Concentrated ownership and complex financing stack (convert notes/warrants and PIPE warrants) elevate governance and dilution considerations; related-party oversight is critical .
  • Additional Observations

    • The Nominating & Corporate Governance Committee recorded “—” meetings in 2024 (structure finalized post-Business Combination), suggesting most committee activity commenced in 2025; investors should evaluate 2025–2026 committee cadence and outputs (skills matrix updates, succession/ESG reporting) .
    • Non-employee director equity is time-based; no performance metrics/TSR tilts for directors, which is standard but offers limited performance linkage beyond share price exposure .

Supporting Data

  • Board and Committee Assignments (2024) | Name | Audit | Compensation | Nominating & Corporate Governance | |---|---|---|---| | Keyvan Mirsaeedi-Farahani | — | — | Chair (X*) |

  • Board Activity and Attendance | Metric | Value | |---|---| | Board meetings in last fiscal year | 5 | | Director attendance | Each director attended ≥75% of Board and applicable committee meetings |

  • Non-Employee Director Compensation (2024 Actual) | Director | Cash Fees ($) | Option Awards ($) | Total ($) | |---|---:|---:|---:| | Keyvan Mirsaeedi-Farahani | 12,500 | — | 12,500 |

  • Non-Employee Director Compensation Program (Adopted Mar 2025) | Component | Amount/Terms | |---|---| | Annual cash retainer | $40,000 | | Committee chair retainers | Audit $20,000; Comp $13,000; N&CG $10,000 | | Committee member retainers | Audit $10,000; Comp $7,000; N&CG $5,000 | | Initial option grant (non-chair) | 90,000 options; vest monthly over 3 years | | Annual option grant (non-chair) | 30,000 options; vest monthly over 1 year | | Chair of the Board option grants | 300,000 initial; 100,000 annual (if serving as Chair) | | Equity plan director cap | $750k/year, $1.0m in initial year (grant-date value) |

  • Related Party Concentration | Holder (Affiliates) | Ownership Components | Beneficial Stake | |---|---|---| | Perceptive Advisors affiliates | 9,675,684 shares + 5,445,069 warrants + 200,902 shares via C2; additional pre-funded/milestone warrants excluded due to 9.99% blocker | 57.55% (beneficial) | | 2025 PIPE (Perceptive affiliates) | 2,190,496 pre-funded warrants + 4,034,997 milestone warrants; ~$4.25m purchase | See transaction table |

Overall: Keyvan brings healthcare investing and strategic expertise with strong credentials, and the Board has formally determined independence. However, his dual status as Perceptive Managing Director and N&CG Chair, combined with Perceptive’s controlling stake and ongoing related-party financings, constitutes a governance sensitivity requiring ongoing monitoring—particularly around director nominations, succession, and ESG oversight. The disclosed Nasdaq audit committee non-compliance further underscores board-level governance risk that investors should track for remediation timelines .