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Jane Henderson

Director at Akero Therapeutics
Board

About Jane Henderson

Independent director (Class I) at Akero Therapeutics since April 2019; age 59 as of April 10, 2025. Background spans nearly 20 years in healthcare investment banking and senior finance roles (CFO/CBO) at multiple biopharma companies; currently CFO of Apogee Therapeutics (since Jan 2023). Education: B.S. in psychology, Duke University. Designated “audit committee financial expert” by Akero’s board, reflecting deep finance and audit expertise .

Past Roles

OrganizationRoleTenureCommittees/Impact
Apogee TherapeuticsChief Financial OfficerJan 2023–presentSenior finance leadership at public biotech; cross-company capital markets exposure
Adagio Therapeutics (Invivyd predecessor)CFO & Chief Business OfficerDec 2020–Nov 2022Led finance and BD through COVID-19 antibody development period
Turnstone BiologicsChief Financial OfficerJun 2018–Dec 2020Built finance function at immuno-oncology company
Voyager TherapeuticsCFO & SVP Corporate DevelopmentJan 2017–Jun 2018Finance + corp dev oversight in gene therapy
Kolltan PharmaceuticalsCFO & SVP Corporate DevelopmentFeb 2013–Nov 2016Company sold to Celldex; executed strategic transaction
Various biopharma + 20 years investment bankingFinance/BD/executive roles; healthcare investment bankingPrior to 2013Deep capital markets and transaction experience

External Roles

OrganizationRoleTenureNotes
Cargo Therapeutics (Nasdaq: CRGX)DirectorCurrentPublic biopharma board seat
Ventus Therapeutics, Inc. (private)DirectorCurrentPrivate biopharma board seat
Sesen Bio (Nasdaq: SESN)DirectorPriorHistorical public board service
IVERIC bio (Nasdaq: ISEE)DirectorPriorHistorical public board service

Board Governance

  • Committees: Audit (Chair); Nominating & Corporate Governance (Member). Audit Committee met four times in FY2024; Nominating & Corporate Governance met two times .
  • Independence: Board determined all non-employee directors, including Henderson, are independent (Nasdaq and SEC standards) .
  • Attendance: Board met four times in 2024; each director attended at least 75% of aggregate board and committee meetings served .
  • Board leadership: Independent chair (Mark T. Iwicki); CEO separate from chair, enhancing oversight .

Fixed Compensation

ComponentPolicy/AmountFY2024 Actual (Henderson)
Board annual cash retainer (member)$40,000 policy $65,000 fees paid in cash
Committee chair—Audit$20,000 policy Included in cash fees
Committee member—Nominating & Corporate Governance$5,000 policy Included in cash fees
Meeting feesNoneN/A
ReimbursementsReasonable travel & out-of-pocket expenses reimbursedAs incurred

Notes: Akero’s non-employee director compensation policy pays cash retainers by role and committee; no separate meeting fees .

Performance Compensation

ComponentGrant/ValueVesting/Performance Metrics
Annual director option grant26,000 options each annual meeting; one-time initial 52,000 options for new directors Annual options vest in full by first anniversary or next annual meeting; initial options vest monthly over 3 years; time-based, no performance conditions
FY2024 option grant (fair value)$434,632 (Henderson) Time-based; no TSR/financial hurdles. Hedging/pledging prohibited for directors

Akero’s director equity is exclusively time-based; no disclosed performance metrics (e.g., TSR, clinical milestones) are tied to director equity grants .

Other Directorships & Interlocks

  • Current public boards: Cargo Therapeutics. Private board: Ventus Therapeutics .
  • Internal interlocks: Audit Committee includes Henderson (Chair), Chou, Heyman, Walmsley; Compensation Committee separate (Iwicki Chair) .
  • Investor-related: Major holders (Wellington, RTW, Janus Henderson, General Atlantic, BlackRock) participated in 2024/2025 offerings; no related-party transactions disclosed involving Henderson .

Expertise & Qualifications

  • Finance/Audit expertise: Designated “audit committee financial expert” .
  • Industry: Extensive biopharma finance and corporate development across gene therapy, immunology, oncology .
  • Education: B.S., psychology, Duke University .

Equity Ownership

MeasureAmountNotes
Total beneficial ownership (shares)96,797All attributable to options exercisable within 60 days
Ownership % of shares outstanding<1%Asterisk indicates <1%
Vested vs. unvested (as of 12/31/2024)70,797 vested; 26,000 unvestedOption detail from director compensation table footnote
Hedging/pledgingProhibitedCompany insider trading policy for directors

Governance Assessment

  • Strengths

    • Independence and financial rigor: Henderson is independent and serves as Audit Chair; designated audit financial expert, indicating strong oversight capability over financial reporting, controls, and auditor interactions .
    • Attendance and engagement: At least 75% attendance in 2024; Audit Committee met four times, indicating regular oversight cadence .
    • Pay structure aligned with market: Cash retainers by role; annual option grants with standardized vesting; no hedging/pledging allowed; minimal perquisites .
    • No related-party transactions: Proxy indicates none since Jan 1, 2024 involving directors (including Henderson) beyond disclosed offerings to institutional holders .
  • Potential investor considerations

    • Ownership alignment: Beneficial ownership is entirely via options and represents <1% of outstanding shares, which may be seen as modest “skin-in-the-game” despite standard director equity grants .
    • External time commitments: Active CFO at Apogee Therapeutics and current external board roles may raise time-commitment questions; however, Akero’s governance guidelines affirm regular review of directors’ outside commitments and sufficiency of time devoted by current directors .
  • Shareholder sentiment signals

    • Say-on-pay outcomes (context): 2024 say-on-pay approval ~95% (strong support) and 2025 advisory vote approval 60,698,263 for vs. 1,199,541 against (continued support for compensation governance), indicating overall confidence in pay practices and board oversight .
  • RED FLAGS

    • None disclosed regarding related-party transactions, hedging/pledging, legal proceedings, or attendance shortfalls for Henderson. The proxy states no material legal proceedings for directors and prohibits hedging/pledging for directors .