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Timothy Rolph

Chief Scientific Officer at Akero Therapeutics
Executive

About Timothy Rolph

Co-founder and Chief Scientific Officer (CSO) of Akero Therapeutics since April 2017; age 71; B.Sc. in Biochemistry (University of London); DPhil in muscle development (University of Oxford). Prior roles include Senior Vice President at Pfizer, where he led cardiovascular, metabolic, and endocrine research and oversaw the FGF21 program; Venture Partner at Apple Tree Partners (2016–2018) . Akero’s compensation philosophy emphasizes pay-for-performance tied to operational milestones, with TSR up to 107.83 in 2024 and net loss of $252.1M; the company notes executives are incentivized on clinical and development metrics rather than revenue or EBITDA as Akero is pre-revenue .

Past Roles

OrganizationRoleYearsStrategic Impact
Pfizer Inc.SVP, Program Value Enhancement; CSO, Cardiovascular/Metabolic/Endocrine1994–2016 Led cardio-metabolic programs; oversaw FGF21 program that underpins Akero’s EFX strategy
Apple Tree PartnersVenture Partner2016–2018 Early-stage company formation; supported translational strategy
Akero TherapeuticsCo-founder, CSO2017–present Scientific leadership for EFX; clinical and manufacturing milestones driving compensation outcomes

External Roles

OrganizationRoleYearsStrategic Impact
Apple Tree PartnersVenture Partner2016–2018 Venture creation and scientific diligence
Pfizer Inc.Senior research leadership1994–2016 Set strategy for cardiovascular/metabolic portfolio; FGF21 program oversight

Fixed Compensation

Metric2020202120222023
Base Salary ($)$414,000 $428,490 $482,000 $506,000
Target Bonus (%)40% 40% 40% 45%
Bonus Paid ($)$207,000 $171,396 $337,400 $216,315 (95% of target)

Performance Compensation

YearMetricWeightingTargetActualPayoutVesting/Notes
2023Phase 3 SYNCHRONY preparation, initiation and first dosingNot disclosedInitiation and dosingAchieved95% of target bonus pool Operational milestones drove payout
2023SYMMETRY Phase 2b read-outs (week 36 main; week 12 expansion)Not disclosedReadoutsAchievedIncluded in 95%
2023CMC/device comparability and FDA alignmentNot disclosedAlignmentAchievedIncluded in 95%
2023Capital raisingNot disclosedFundraisingAchievedIncluded in 95%
2022HARMONY Phase 2b readout; SYMMETRY enrollment; API release; Phase 3 filings; financingNot disclosedMulti-metricAchievedReflected in 2022 payouts
2021Multiple clinical, regulatory, manufacturing readiness goalsNot disclosed100% base goalsAchieved100% of target

Equity Ownership & Alignment

  • Policy prohibits hedging and pledging; no approvals sought or granted for pledging by NEOs; ESPP participation available; clawback policy effective 9/13/2023 .

Beneficial Ownership Trend

As-of DateShares Beneficially Owned% of Outstanding
Apr 9, 2020294,228 1.02%
Apr 5, 2021411,309 1.18%
Apr 4, 2022521,761 1.48%
Apr 6, 2023570,436 1.20%
Apr 2, 2024585,792 <1% (*)

Vested vs. Unvested Detail (Outstanding Equity Awards at 12/31/2023)

AwardExercisable (#)Unexercisable (#)Strike ($)ExpirationRSUs Unvested (#)
Options (12/09/2022)21,594 64,785 42.95 12/09/2032
Options (12/08/2023)146,237 19.87 12/08/2033
Options (12/08/2021)43,610 43,611 21.10 12/08/2031
Earlier options (various 2019–2021 tranches)Multiple lines Multiple lines 0.62–28.35 2028–2031
RSUs (12/08/2023 grant)32,497
RSUs (12/09/2022 grant)14,397

Vesting schedules: options vest monthly over 48 months; 2022 RSUs vest quarterly over 16 quarters; 2023 RSUs vest semi-annually over 4 years .

Recent Grants (structure)

Grant DateInstrumentSharesVestingStrike ($)
12/08/2023Stock Options146,237 Monthly over 48 months 19.87
12/08/2023RSUs32,497 Semi-annual over 4 years
12/09/2022Stock Options86,379 Monthly over 48 months 42.95
12/09/2022RSUs19,195 Quarterly over 4 years
12/08/2021Time-based + Performance-based Options87,221 + 87,221 Time-based monthly; performance options tied to operational goals 21.10

Employment Terms

  • Agreement effective at IPO (May 2019). Without change-in-control: 9 months base salary; up to 9 months COBRA at active-employee rate; standard at-will employment . With change-in-control (within 12 months post-CIC, double-trigger): lump sum 12 months base + 1x target bonus; full acceleration of all time-based equity awards; up to 12 months COBRA at active-employee rate .

Estimated Payments (12/31/2023 assumptions)

ScenarioCash SeveranceBonus SeveranceCOBRAEquity AccelerationTotal
Termination without Cause (no CIC)$394,500 $1,599 $396,099
Termination without Cause or Resign for Good Reason (within 12 months of CIC)$526,000 $236,700 $2,132 $607,030 $1,371,862

Additional policies: clawback on restatements per SEC/Nasdaq; no tax gross-ups for golden parachutes; Section 409A compliance; no SERP/defined benefit plans; limited perquisites; equity grant timing controls to avoid MNPI .

Investment Implications

  • Alignment and retention: Rolph’s increasing beneficial ownership through 2023 and continued unvested equity (options/RSUs vesting through 2027–2028) signal ongoing alignment and retention incentives; hedging/pledging prohibited reduces forced-sale risk .
  • Change-in-control economics: Double-trigger acceleration and 12 months base + 1x bonus imply moderate CIC leverage; full acceleration of time-based equity awards could create event-driven supply if transaction closes; monitor M&A chatter and proxy disclosures .
  • Performance linkage: Bonus outcomes tied to operational milestones (Phase 3 initiation, enrollment, FDA alignment, manufacturing readiness, financing) rather than GAAP metrics; company achieved 95% of goals in 2023 and 100% in 2024, indicating execution strength under scientific leadership .
  • Option strike stack: Significant 2023 options at $19.87 and 2022 options at $42.95 create layered intrinsic value sensitivity; watch share price relative to strikes to gauge potential exercise/sale pressure as tranches vest .
  • Governance and pay risk: Strong say-on-pay (95% approval), use of independent consultant (Pearl Meyer), and clawback policy reduce compensation controversy risk; absence of tax gross-ups and pledging bans are shareholder-friendly .